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HIVandHepatitis.com Coverage of Highlights from the
56th Annual Meeting of the American
Association for the Study of Liver Diseases

 November 11 - 15, 2005 San Francisco, California
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Note: Unless otherwise stated, all references are to the Abstracts of the 56th Annual Meeting of the American Association for the Study of Liver Diseases, November 11 - 15, 2005, San Francisco, CA. Please note that this coverage is not associated officially or unofficially with the American Association for the Study of Liver Diseases.
Contributors: Ronald Baker, PhD and Marina Núñez , MD, PhD
Hepatitis C
New Experimental HCV Drugs in Development
HCV Protease Inhibitor SCH-503034 / Combo Treatment SCH-503034
HCV Protease Inhibitor VX-950
Valopicitabine (NM 283)
Consensus Interferon + Gamma Interferon +/- Ribavirin
Albuferon Plus Ribavirin
High-dose (double dose) Pegasys + Ribavirin

HIV-HCV Coinfection

FDA-approved HCV Treatments
PegIntron + Ribavirin
Pegasys + Ribavirin

African Americans
Pharmacokinetics

Genotypes
Adverse Events
Nonresponders
Viral Kinetics
Super Responders
Sustained Virologic Response (SVR)
Ribavirin - Flat dosing and Weight-based dosing
High dose peginterferon alfa-2b (PegIntron)
Hepatitis B
FDA-approved HBV Treatments
Adefovir dipivoxl (Hepsera)
Epivir-HBV (Lamivudine)

Pegasys (peginterferon alfa-2a)
Entecaivr (Baraclude)
Intron A (interferon alfa-2a)

Adverse Events
Adefovir dipivoxil Resistance
Cirrhosis
Cost Effectiveness
Epivir-HBV Resistance
Experimental Treatments for HBV
Sustained Virologic Response (SVR)
Histologic Improvement/Response
Genotyping
HBeAg negative/positive
HBV Viral Suppression
Salvage Therapy
Fibrosis

Weight-based and
   Flat dosing of ribavirin

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



















































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FDA-approved Treatments for HBV
Baraclude
Epivir-HBV
Hepsera
Intron A
Pegasys
FDA-approved Treatments for HCV
Intron A
Roferon
Infergen
Pegasys
PEG-Intron
Pegasys + Copegus
PEG-Intron + Rebetol
Intron A + Rebetol
Roferon A + Ribavirin