HIV and Hepatitis.com Coverage of the
15th Conference on Retroviruses and Opportunistic Infections (CROI 2008)
 February 3 - 6, 2008, Boston, MA
The material posted on HIV and Hepatitis.com about CROI 2008 is not approved
by nor is it a part of CROI 2008.

LIbrary of Slides and Posters


Switching from Combivir [CBV] (AZT/3TC) to Truvada [TVD] (TDF/FTC) Preserves Limb Fat: Results of a DEXA Sub-Study of a 48 Week Randomised Study
G Moyle and others. CROI 2008.

DELPHI Darunavir EvaLuation in Pediatric HIV-1- Infected treatment-experienced patients
R Bologna and others. CROI 2008.

Characterization of virologic failures on darunavir/ritonavir in the randomized, controlled, Phase III TITAN trial in treatment-experienced patients
S De Meyer and others. CROI 2008.

Pharmacokinetic-pharmacodynamic analyses of once-daily darunavir in the ARTEMIS study
V Sekar and others. CROI 2008.

Long-acting TMC278, a parenteral depot formulation delivering sustained NNRTI plasma concentrations in preclinical and clinical settings
G van’t Klooster and others. CROI 2008.

DUET-1:Week 48 results of a Phase III randomized double-blind trial to evaluate the efficacy and safety of etravirine (ETR; TMC125) versus placebo in 612 treatment-experienced HIV-1-infected patients
R Haubrich and others. CROI 2008.

DUET-2:Week 48 results of a Phase III randomized double-blind trial to evaluate the efficacy and safety of etravirine (ETR; TMC125) versus placebo in 591 treatment-experienced HIV-1-infected patients
M Johnson and others. CROI 2008.

Pharmacokinetics of the next-generation NNRTI etravirine (ETR; TMC125) in HIV-infected children between 6 and 17 years, inclusive
T Kakuda and others. CROI 2008.

Pharmacokinetics and pharmacodynamics of the NNRTI etravirine (ETR; TMC125) in treatment-experienced HIV-1-infected patients: pooled 24-week results of DUET-1 and DUET-2
T Kakuda and others. CROI 2008.

Prevalence of etravirine (ETR; TMC125) resistance-associated mutations in a large panel of clinical isolates
G Picchio and others. CROI 2008.

Efficacy and Safety of Abacavir/Lamivudine Compared to Tenofovir/Emtricitabine in Combination with Once-Daily Lopinavir/Ritonavir through 48 Weeks in the HEAT Study
K Smith and others. CROI 2008. Copyright GlaxoSmithKline. Used with permission, 2008.

Resistance Profile of the Integrase Inhibitor S/GSK-364735
T Yoshinaga and others. CROI 2008. Copyright GlaxoSmithKline. Used with permission, 2008.

A phase I study to explore the activity and safety of SCH 532706, a small molecule chemokine receptor-5 (CCR5) antagonist in HIV-1 infected subjects.
S Pett and others. CROI 2008

Effect of Virus Concentration on in vitro Measurement of Phenotypic Resistance to the CCR5 Antagonist Vicriviroc.
C Buontempo and others. CROI 2008.

The Effect of Vicriviroc Upon Viral Load in HIV/HCV Co-infected Patients Receiving a Ritonavir-containing Protease Inhibitor Regimen.
G Fätkenheuer and others. CROI 2008.

48-Week Results from BENCHMRK-1, a Phase III Study of Raltegravir (RAL) in Patients Failing Antiretroviral Therapy (ART) with Triple-Class Resistant HIV-1.
D Cooper and others. CROI 2008.

48-Week Results from BENCHMRK-2, a Phase III Study of Raltegravir (RAL) in Patients Failing Antiretroviral Therapy (ART) with Triple-Class Resistant HIV-1.
R Steigbige and others. CROI 2008.

Vicriviroc, a Next Generation CCR5 Antagonist, Exhibits Potent, Sustained Suppression of Viral Replication in Treatment-Experienced Adults: VICTOR-E1 48-week Results.
B Zingman and others. CROI 2008.

Vicriviroc in Combination Therapy With an Optimized Antiretroviral Regimen for Treatment-Experienced Subjects: The VICTOR-E1 Trial.
B Zingman and others. CROI 2008.

Bone Mineral Density (BMD) 96 Weeks after Antiretroviral Therapy (ART) Initiation: A Randomized Trial Comparing Efavirenz (EFV)-Based Therapy to a Lopinavir/ ritonavir (LPV/r)-Containing Regimen with Simplification to LPV/r Monotherapy.
T Brown and others. CROI 2008.

Study M05-730 Primary Efficacy Results at Week 48: Phase 3, Randomized, Open-Label Study of Lopinavir/ritonavir (LPV/r) Tablets Once Daily (QD) versus Twice Daily (BID), Co-Administered with Tenofovir DF (TDF) + Emtricitabine (FTC) in Antiretroviral-Naïve (ARV) HIV-1 Infected Subjects.
J Gathe and others. CROI 2008.

Prevalence, Mutational Patterns and Phenotypic Correlates of the L76V Protease Mutation in Relation to LPV Associated Mutations.
M Norton and others. CROI 2008.

Lopinavir/ritonavir (LPV/r) 500/125 mg BID Plus Efavirenz Approximate the Pharmacokinetic Exposure of LPV/r 400/100 mg BID Administered Alone in Healthy Adult Subjects.
J Ng and others. CROI 2008.

Impact of a 48-week Lopinavir/r Monotherapy on HIV1-DNA in Blood Cells in the MONARK Trial.
V Avettand-Fenoel and others. CROI 2008.

Multicenter, Retrospective Study of Incidence and Predictors of Adverse Events Associated With Nevirapine Use in a Cohort of Pregnant and Nonpregnant Women Treated at 3 Urban HIV Clinics in the United States
E Aaron and others. CROI 2008.

Pharmacokinetic Interaction Between Tipranavir/Ritonavir and Rosuvastatin
P Pham and others. CROI 2008.


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


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