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Roche and InterMune to Collaborate on HCV Protease Inhibitor ITMN-191

InterMune announced last week that it has entered into a collaborative agreement with Roche Laboratories to develop and commercialize products from InterMune's HCV protease inhibitor program.

The agreement includes InterMune's lead candidate compound ITMN-191, which is expected to enter clinical trials before the end of 2006. The two companies will also collaborate on a research program for second-generation HCV protease inhibitors.

Roche currently produces one brand of pegylated interferon plus ribavirin (Pegasys plus Copegus), which is the current standard-of-care treatment for chronic hepatitis C.

InterMune added that Roche will exclusively license ITMN-191 and have the right to exclusively license further HCV protease inhibitor candidates resulting from the collaboration.

Upon closing, InterMune will receive an upfront payment of $60 million, and -- assuming the successful development and commercialization of ITMN-191 -- could receive up to $470 million in milestones payments.

10/24/06

Source
www.MarketWatch.com. InterMune, Roche to Collaborate on Protease Inhibitor. October 20, 2006.

FDA-approved
Monotherapies for HCV
Intron A
Roferon

Infergen

Pegasys

PEG-Intron

FDA-approved
Combination
Therapies
for HCV
Pegasys + Copegus
PEG-Intron + Rebetol
Intron A + Rebetol
Roferon A + Ribavirin

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

FDA-approved
Monotherapies for HCV
Intron A
Roferon

Infergen

Pegasys

PEG-Intron

FDA-approved
Combination
Therapies
for HCV
Pegasys + Copegus
PEG-Intron + Rebetol
Intron A + Rebetol
Roferon A + Ribavirin