Are IL28B Gene Variations Associated with Outcomes in People with Hepatitis B?
- Details
- Category: HBV Treatment
- Published on Friday, 12 November 2010 12:48
- Written by Liz Highleyman
IL28B gene patterns may influence response to interferon therapy for hepatitis B, but this is not as straightforward as it is for hepatitis C, according to a set of studies presented at the recent American Association for the Study of Liver Diseases "Liver Meeting" (AASLD 2010) in Boston. Two analyses suggested that people with the protective rs12979860 C/C pattern were more likely to achieve sustained virological suppression with interferon, but less likely to experience HBeAg seroconversion. A third study, however, found no link between rs12979860 pattern and hepatitis B or HIV persistence or progression.
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