HIV/AIDS Topics HIV Treatment HIV Clinical Trials
Gilead Starts Phase 2 Trial of Tenofovir Pro-drug GS-7340
- Details
- Category: Experimental HIV Drugs
- Published on Friday, 27 January 2012 00:00
- Written by Press Release
Gilead Sciences this week announced the start of a new Phase 2 clinical trial that will compare an all-in-1 combination pill containing GS-7340 -- a pro-drug of tenofovir (Viread, also in the Truvada and Atripla coformulations) that can be taken in lower doses -- versus the experimental Quad combo containing the same drugs with tenofovir itself.
Tobira Recruiting for Trial of CCR2/CCR5 Entry Inhibitor Cenicriviroc
- Details
- Category: Experimental HIV Drugs
- Published on Friday, 30 September 2011 00:00
- Written by Press Release
Tobira Therapeutics has initiated a clinical trial to test its investigational CCR2/CCR5 antagonist HIV entry inhibitor cenicriviroc (TBR-652).
FDA Pain Patch Decision: Making a 'Sophie's Choice' with People's Lives
- Details
- Category: HIV Clinical Trials
- Published on Monday, 14 February 2011 00:00
- Written by Matt Sharp
At the Food and Drug Administration (FDA) advisory hearing on Thursday, February 9, a panel of scientists and clinicians voted unanimously not to recommend approval of the Qutenza capsaicin patch for HIV neuropathy pain, based on data from 2 clinical trials. As the sole patient representative on the panel, it was an incredibly demoralizing experience. 
Large Vaccine Study Will Look at HIV Prevention as well as Disease Progression
- Details
- Category: HIV Clinical Trials
- Published on Tuesday, 09 August 2011 00:00
- Written by Press Release
A large ongoing HIV vaccine study will now test whether a prime-boost candidate can prevent infection as well as lower viral load among people infected, based on the promising protective effect seen so far, the National Institutes of Allergy and Infectious Diseases (NIAID) announced.
Counting Your Chickens: Reliance on Unreliable Information about Medical Studies
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- Category: HIV Clinical Trials
- Published on Monday, 10 January 2011 00:00
- Written by Matt Sharp
Over the years, medical news coming from major media outlets and the Internet has not always been reliable. Some reports have ranged from completely inaccurate to skewed to the point of being crazy. And today, many people post and re-post misleading news until it goes viral, spreading false information around the globe.
New Multinational START Trial Explores When to Begin Antiretroviral Therapy
- Details
- Category: HIV Clinical Trials
- Published on Thursday, 10 March 2011 16:00
- Written by Liz Highleyman
The long-awaited START (Strategic Timing of Antiretroviral Treatment) trial is now recruiting participants in an effort to determine the best time to initiate antiretroviral therapy (ART), an issue that remains controversial. In this international Phase IV trial, asymptomatic HIV positive adults with CD4 T-cell counts above 500 cells/mm3 -- the threshold for starting therapy in the current U.S. treatment guidelines -- will be randomly assigned to either begin ART immediately or wait until their CD4 count falls to 350 cells/mm3.
Town Hall Meeting Explores Future Directions for HIV Clinical Trials
- Details
- Category: HIV Clinical Trials
- Published on Monday, 15 November 2010 16:00
- Written by AIDSinfo
On October 26, the National Institute of Allergy and Infectious Diseases (NIAID) hosted a "town hall" meeting to gather input on how best to restructure the federal HIV clinical trials network to account for changes in the epidemic, including greater efficacy of antiretroviral therapy (ART), better overall patient health, and increased frequency of non-AIDS conditions.
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