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Antiretroviral Treatment Lowers Risk of Non-AIDS Illness in People Newly Diagnosed with HIV

Non-AIDS conditions are a significant cause of illness and death for people recently diagnosed with HIV, but starting antiretroviral therapy (ART) can reduce the likelihood of non-AIDS events including psychiatric and kidney problems, according to study findings published in the September 26, 2012, advance online edition of AIDS.alt

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ICAAC 2012: New Tenofovir Pro-drug Matches Potency of Original Version but with Less Toxicity

Tenofovir alafenamide fumarate (TAF), the tenofovir pro-drug formerly known as GS-7340, has antiviral potency similar to that of tenofovir disoproxil fumarate (TDF), and a new "quad" formulation containing TAF works as well as the Stribild single-tablet regimen (elvitegravir/cobicistat/TDF/emtricitabine) but appears to be easier on the bones and kidneys, according to recently released data.alt

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Resources for People with HIV and Hepatitis and Providers in Disaster Areas

During disasters such as Hurricane Sandy, people with chronic medical conditions including HIV and viral hepatitis will be among those displaced and requiring emergency care. Government agencies offer a number of resources for people with these and other chronic conditions, healthcare providers, and others who provide emergency and disaster-related services.

[Editor's note: This resource list will be updated as further information becomes available.]
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HHS Updates Antiretroviral Treatment Guidelines for Children with HIV

On November 1, 2012, the U.S. Department of Health and Human Services (HHS) released the latest revision of its Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection. Key changes include new information on HIV diagnosis of children, when to start treatment, and discussion of newer antiretroviral drugs. alt

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High-dose Vitamins Do Not Improve HIV Outcomes or Lower Mortality, but May Harm Liver

High-dose multivitamins do not reduce HIV disease progression or risk of death when added to combination antiretroviral therapy (ART), but may contribute to liver toxicity, according to a study in Tanzania described in the October 17, 2012, Journal of the American Medical Association.alt

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Raltegravir (Isentress) Can Cause Central Nervous System Side Effects for People with HIV

The HIV integrase inhibitor raltegravir (brand name Isentress) is generally safe and well-tolerated, but it can cause central nervous system (CNS) symptoms such as insomnia, dizziness, and mood changes, especially when used with other drugs that raise its levels in the body, researchers reported in the October 1, 2012, advance online edition of AIDS. alt

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IDWeek 2012: Simplified Protease Inhibitor Monotherapy Fails to Maintain HIV Suppression

A simplified regimen of lopinavir/ritonavir (Kaletra) monotherapy did not keep HIV viral load fully suppressed after patients switched from a standard 3-drug antiretroviral regimen, researchers reported at the IDWeek 2012 conference last week in San Diego.alt

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