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Second Potentially Cured Baby Has HIV Relapse Soon After Stopping Treatment

An Italian child who started antiretroviral treatment soon after birth and had undetectable plasma viral load, no apparent HIV DNA, and tested HIV antibody negative nevertheless experienced viral rebound shortly after a treatment interruption, once again disappointing hopes for a cure, researchers reported in the October 4 edition of The Lancet.

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HIVMA Issues Guidelines for Managing Chronic Kidney Disease in People with HIV

The HIV Medical Association (HIVMA) of the Infectious Diseases Society of America (IDSA) has released updated recommendations for HIV positive people with chronic kidney disease. The guidelines, published in the September 17 issue of Clinical Infectious Diseases, state that antiretroviral therapy (ART) is beneficial for such patients, but they should avoid tenofovir (Viread, also in the Truvada, Atripla, Complera, and Stribild coformulations), which can cause kidney impairment.

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Monkey Transplant Study Rules Out Possible HIV Cure Mechanism

Macaque monkeys that received transplants of their own stem cells after undergoing intensive radiation that killed off their existing SHIV-infected immune cells experienced viral rebound soon after stopping antiretroviral drugs, indicating that pre-transplant "conditioning" was not solely responsible for the only known case of a person cured of HIV.

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UNAIDS: "Fast Track" Strategy Could Help End AIDS Epidemic by 2030

A rapid acceleration of HIV prevention and treatment efforts over the next 5 years directed at people most at risk in high prevalence areas could help turn the tide in the AIDS epidemic, according to participants at a recent high-level meeting during the 69th United Nations General Assembly. If fully implemented, this approach could potentially prevent 18 million new HIV infections and 11 million deaths by 2030, as well as reducing future costs.

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HIV Superinfection May Boost Viral Load but Does Not Worsen Disease Progression

Superinfection with a second strain of HIV may lead to a more rapid increase in plasma HIV RNA levels, but apparently does not contribute much to CD4 T-cell loss or disease progression, according to a study published in the September 24 edition of AIDS.

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USCA 2014: U.S. Conference on AIDS Underway in San Diego

The 18th annual U.S. Conference on AIDS, sponsored by the National Minority AIDS Council, is taking place this week in San Diego. While other conferences focus on new data about antiretroviral therapy and biomedical prevention, USCA emphasizes the social, economic, and cultural aspects of HIV/AIDS.

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HIV Pandemic Likely Originated in Kinshasa, Spread Via New Transportation Routes

Kinshasa, in what is now the Democratic Republic of Congo, was likely the focus of early HIV-1 transmission beginning in the 1920s, leading to the wider global pandemic starting in the 1960s as railroad and river transportation became more widely used, according to a study published in the October 3 edition of Science.

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