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Gilead Starts Phase 2 Trial of Tenofovir Pro-drug GS-7340

Gilead Sciences this week announced the start of a new Phase 2 clinical trial that will compare an all-in-1 combination pill containing GS-7340 -- a pro-drug of tenofovir (Viread, also in the Truvada and Atripla coformulations) that can be taken in lower doses -- versus the experimental Quad combo containing the same drugs with tenofovir itself.alt

Pets and Parenthood Help Women Cope with HIV

Identification with their role as a mother, grandmother, or pet owner helped women with HIV cope with having a chronic disease, according to a study published in the January 2012 online edition of Women's Health Issues.alt

FDA Approves New Tenofovir (Viread) Formulation and Dosing Regimen for HIV+ Children

The U.S. Food and Drug Administration (FDA) and Gilead Sciences last week announced the approval of a new oral powder formulation and new strength tablets of tenofovir (brand name Viread) -- one of the most widely used nucleoside reverse transcriptase inhibitors (NRTIs) in combination antiretroviral regimens -- as well as new dosing recommendations for HIV positive children and adolescents age 2 through 18 years.alt

Nevirapine for 6 Months during Breast-feeding Prevents Perinatal HIV Transmission

Treating babies with nevirapine (Viramune) for 6 months while breast-feeding significantly reduced the risk of mother-to-child HIV transmission, though it did not alter the likelihood of infant mortality, according to a study of HIV positive African women and their babies described in the January 21, 2012, issue of The Lancet.alt

Oral HIV Tests May Be Less Accurate than Blood Tests

Oral HIV antibody testing is quick and convenient, but this method is not quite as accurate as blood testing in low-prevalence settings, being more likely to produce false-positive results, according to a study review and meta-analysis described in the January 24, 2012, online edition of The Lancet Infectious Diseases.alt

UPCOMING 1/25/12: Administration on Aging 'Graying of HIV/AIDS' Webinar

The U.S. Administration on Aging (AoA) will host a free webinar entitled “The Graying of HIV/AIDS: Community Resources for the Aging Services Network” on Wednesday, January 25, from 2:00 to 3:00 pm Eastern Standard Time.alt

Low but Detectable Viral Load Can Lead to HIV Rebound

People with HIV RNA levels < 50 copies/mL but detectable may still experience viral rebound while on antiretroviral therapy, and should consider switching to a more effective regimen if low-level viral load persists, according to a study described in the January 11, 2012, advance online edition of Clinical Infectious Diseases.alt