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Socioeconomic and Racial Disparities May Drive HIV Infection among Young Gay and Bisexual Men

Young black or mixed-race men who have sex with men were more likely to be newly infected with HIV than gay and bisexual men of other racial/ethnic groups, according to a study from New York City described in the March 27 advance edition of Journal of Acquired Immune Deficiency Syndromes. Living in an area with higher HIV prevalence, lower perceived socioeconomic status, and starting sex at a younger age were also associated with higher risk of infection.

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June 5 is National HIV/AIDS Long-Term Survivors Awareness Day

Friday, June 5, is the second annual National HIV/AIDS Long-Term Survivor Awareness Day (NHALTSAD). Coinciding with the anniversary of the first reported casesof the disease that would come to be known as AIDS, in 1981, the day aims to raise awareness about people living with HIV since the early years of the epidemic, many of whom are facing new and unexpected challenges as they age.

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First START Results Show Early HIV Treatments Reduces Risk of Illness and Death

Long-awaited interim findings from the START trial have shown that people with HIV who were randomly assigned to start antiretroviral therapy (ART) while their CD4 count was above 500 cells/mm3 had a 53% lower risk of AIDS-related and non-AIDS illnesses and deaths compared to those who waited until their count fell below 350 cells/mm3, according to an announcement today from the National Institute of Allergy and Infectious Diseases.

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Tenofovir Alafenamide Subdermal Implant Shows Promise for HIV PrEP in Beagle Study

A sustained-release subdermal implant was able to maintain consistently high levels of tenofovir in cells with no adverse events in an animal study, offering proof-of-concept that an implant may be a good candidate for HIV pre-exposure prophylaxis, or PrEP, according to a study described in the April 20 edition of Antimicrobial Agents and Chemotherapy.

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Do Sex and HIV/HCV Coinfection Affect Response to Antiretroviral Treatment?

HIV-positive men and women coinfected with hepatitis C virus (HCV) showed impaired CD4 T-cell restoration after starting antiretroviral therapy (ART) and had a 40% greater risk of death than people with HIV alone, though they were equally likely to achieve HIV viral suppression, according to study findings published in the May 18 advance edition of AIDS Patient Care and STDs.

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Truvada PrEP Causes Only Minimal Bone Loss, Raltegravir Easier on Bones than PIs

Use of tenofovir/emtricitabine (Truvada) for HIV pre-exposure prophylaxis (PrEP) was associated with a small decrease in bone mineral density that stabilized after the first 6 months, according to study findings reported in the April 23 edition of Clinical Infectious Diseases. Related research showed that HIV-positive people starting an antiretroviral regimen containing the integrase inhibitor raltegravir (Isentress) experienced less bone loss than those taking protease inhibitors.

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FDA Reduces Gay Blood Donation Ban to 1 Year After Sex, Critics Say It's Still Discriminatory

On May 12 the U.S. Food and Drug Administration (FDA) issued draft guidance stating that men who have sex with men should wait to donate blood until 12 months after their last sexual contact with another man. This is an improvement over the previous policy of lifetime deferral, but some advocates argue that the new regulations still discriminate against gay and bisexual men.

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