HIV / AIDS
Elvitegravir Continues to Look Good at 2 Years
- Details
- Category: HIV Treatment
- Published on Tuesday, 13 December 2011 00:00
Gilead Sciences announced last week that its experimental integrase inhibitor elvitegravir continued to suppress HIV viral load as well as raltegravir (Isentress) in combination with a boosted protease inhibitor at 96 weeks in a Phase 3 study.
Occasional Marijuana Smoking Does Not Cause Long-Term Lung Damage
- Details
- Category: Alternative & Complementary Therapy
- Published on Saturday, 10 December 2011 00:00
Infrequent smoking of cannabis over prolonged periods did not lead to a decrease in pulmonary function, according to a 20-year study reported in the January 11, 2012, Journal of the American Medical Association. These findings suggest that occasional recreational use of marijuana does not cause lung damage similar to that seen with regular tobacco use, but more study is needed of people who use medical marijuana more frequently.
Activists Launch Survey for People with HIV about Cure Research Risk
- Details
- Category: Search for a Cure
- Published on Friday, 09 December 2011 00:00
Activists with Project Inform, the Program for Wellness, and the Treatment Action Group are asking HIV positive people to participate in a brief online survey about participation in clinical trials and opinions about the potential risks and benefits of cure-related research.
CDC Announces $300 Million in HIV Prevention Funding Grants
- Details
- Category: HIV Prevention
- Published on Saturday, 10 December 2011 00:00
The U.S. Centers for Disease Control and Prevention (CDC) last week announced the first round of grant awards to state and local health departments as part of its new "high-impact" HIV prevention initiative. The CDC launched the initiative earlier this year, emphasizing prevention efforts that target the most heavily impacted regions and population groups -- in particular young black gay men -- and are supported by scientific evidence.
Monkey Study at HIV Persistence Workshop Offers Hope for Functional Cure
- Details
- Category: Search for a Cure
- Published on Friday, 09 December 2011 00:00
Researchers meeting this week at the International Workshop on HIV Persistence, Reservoirs and Eradication Strategies in St Maarten heard about a small study of macaque monkeys which showed that a multidrug strategy targeting the viral reservoir lowered levels of SIV (a simian virus similar to HIV) and allowed the animals to remain off antiretroviral drugs for 3 months -- in effect a short-term functional cure.
Experimental Vaccine Offers Partial Protection against HIV-Related Virus in Monkeys
- Details
- Category: HIV Vaccines
- Published on Saturday, 10 December 2011 00:00
An investigational adenovirus prime-poxvirus booster vaccine regimen reduced the likelihood of infection in rhesus monkeys exposed to simian immunodeficiency virus (SIV), a monkey virus similar to HIV, researchers reported in the January 4, 2011, advance online edition of Nature. The vaccine reduced infection risk by about 80% compared with placebo, and monkeys that did become infected had lower viral loads.
Truvada Drug Levels in Vaginal and Rectal Tissue Offer Clues to HIV PrEP Puzzle
- Details
- Category: HIV Prevention
- Published on Friday, 09 December 2011 00:00
The 2 drugs in the Truvada pill -- tenofovir and emtricitabine -- reach different concentrations in human cervical, vaginal, and rectal mucosa tissues and fluids, according to new research published in the December 7, 2011, issue of Science Translational Medicine. Lower drug levels in the female genital tract suggest that women may need higher doses to achieve a prophylactic effect, which may help explain conflicting results from some recent biomedical HIV prevention trials. 
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