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Recent Studies Shed Light on Cancer Among People with HIV

Starting antiretroviral therapy (ART) with a low CD4 count raises the likelihood of certain cancers, but others increase with longer time on therapy, reflecting a rising risk associated with older age, according to a recently published study. Other new research revealed increases in malignancies related to viral infections and a higher risk of Kaposi sarcoma even after immune restoration.

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Neurocognitive Impairment Common Among Youth with HIV

Approximately two-thirds of HIV positive young adults showed evidence of HIV-associated neurocognitive disorders (HAND), including impaired memory and fine motor control, according to a report in the August 21, 2013, advance edition of the Journal of Adolescent Health.

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ADAP Crisis Task Force and ViiV Agree on Discounted Price for Dolutegravir

The ADAP Crisis Task Force (ACTF) announced this week that it has negotiated an agreement with ViiV Healthcare to provide the newly approved integrase inhibitor dolutegravir (Tivicay) to AIDS Drug Assistance Program (ADAP) recipients for less than the wholesale cost.

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Early Time-limited Treatment Leads to Better Outcomes for Infants with HIV

Infants with HIV who start antiretroviral therapy (ART) immediately after birth had a lower risk of disease progression or death and were able to safely interrupt treatment longer than children who started ART later, according to findings from the long-running CHER study published in the August 22, 2013, advance online edition of The Lancet.

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IAS 2013: HIV May Be Present in Semen Despite Undetectable Blood Viral Load

Gay men with HIV can shed the virus in their semen even when they are on antiretroviral therapy (ART) with fully suppressed blood plasma viral load, according to a longitudinal French study presented at the recent 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.

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Increased Risk of AIDS-defining Illnesses Seen Even at CD4 Counts of 500-750

HIV positive people with CD4 T-cell counts in the 500-749 cells/mm3 range still have a higher risk of AIDS-defining illnesses -- especially cancers -- compared to those with more than 1000 cells/mm3, although the risk is quite low, according to a study published in the August 6, 2013, advance edition of Clinical Infectious Diseases. These findings offer further evidence of the benefits of prompt antiretroviral treatment.

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Preventive Antibiotics for Tuberculosis Lower Risk of Death for People with HIV

Increased screening for tuberculosis (TB) and prophylactic treatment with isoniazid significantly reduced the incidence of active TB disease as well as mortality among patients treated at HIV clinics in Brazil, according to a study published in the August 14, 2013, advance edition of Lancet Infectious Diseases. This is the first evidence that a community-wide effort can prevent people coinfected with HIV and TB from developing active TB disease.

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