HIV and Hepatitis C Highlights from CROI 2014

Latest Positive Pulse Newsletter

In this overview, Paul Sax from Harvard Medical School and Mark Sulkowski from Johns Hopkins School of Medicine discuss selected highlights from the recent Conference on Retroviruses and Opportunistic Infections (CROI 2014), focusing on antiretroviral therapy, HIV cure research, and new treatments for hepatitis C and HIV/HCV coinfection.


Rilpivirine Is Associated with Less Blood Fat Elevation than Efavirenz

People with HIV who started first-line treatment with a regimen containing rilpivirine (Edurant, also in the Complera coformulation) had smaller blood lipid increases and were less likely to have abnormal levels than those who started on efavirenz (Sustiva, also in the Atripla coformulation), according to 2-year data from the ECHO and THRIVE trials published in the April 11 online edition of Clinical Infectious Diseases.


Is HIV Transmission Risk Really Near Zero If HIV+ Heterosexual Partners Are on ART?

Serodiscordant heterosexual couples in which the positive partner has been on combination antiretroviral therapy (ART) for more than 6 months may have an HIV transmission risk as high as 13 per 100,000 sex acts -- but the risk could also be zero -- according to an estimate based on a systematic review described in the April 9 online edition of Clinical Infectious Diseases.


People with HIV Have Higher Bone Fracture Risk in Danish Study

Being HIV positive was associated with a nearly 3-fold greater likelihood of bone fractures overall -- and a 9-fold higher risk of hip and spine fractures -- compared with HIV negative people, according to results from a large Danish population study described in the May 1 Journal of Acquired Immune Deficiency Syndromes.


March 20 Is National Native HIV/AIDS Awareness Day

Tuesday, March 20, marks the 8th annual observation of National Native HIV/AIDS Awareness Day (NNHAAD), an occasion to raise awareness about HIV and AIDS among American Indians, Alaska Natives, and Native Hawaiians.


San Francisco HIV Forum Asks: Is Undetectable the New Negative?

More than 100 participants packed the Eureka Valley Recreation Center in San Francisco on May 20 for the latest Real Talk discussion of new HIV prevention strategies including pre-exposure prophylaxis (PrEP) and antiretroviral treatment as prevention.


People with HIV Have Higher Risk of Melanoma Skin Cancer

People with HIV -- especially those with light skin -- continue to have a significantly increased risk of developing melanoma in the era of highly effective antiretroviral therapy, and should protect themselves from the sun, according to a meta-analysis published in the April 16 edition of the open-access journal PLoS ONE.