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HIV / AIDS

Study Sheds Light on Residual Viral Load

Residual low-level HIV plasma viremia correlates with size of the CD4 T-cell reservoir, but not immune activation markers. alt

Monkey T-Cells Don't Express Co-receptor

Sooty mangabey monkeys with SIV do not experience disease progression because their CD4 T-cells express little of the CCR5 co-receptor the virus requires to enter cells. alt

CDC Reports Extended HIV/AIDS Surveillance Data

More than 1.1 million people in the U.S. were living with HIV at the end of 2008, with 20% not knowing their status. But the burden is unevenly distributed, with 50% of cases among gay men and higher incidence among African-Americans. alt

HIV Coreceptor Tropism Affects Treatment Outcomes

HIV strains that use the CXCR4 co-receptor are associated with higher risk of virological failure on antiretroviral therapy than those using CCR5, according to a recent Spanish study. alt

New HRSA Guide for HIV/AIDS Clinical Care

An updated version of the Health Resources and Services Administration (HRSA) Guide for HIV/AIDS Clinical Care is now available free online.

Tobira Starts Phase 2b Cenicriviroc Trial

Tobira Therapeutics recently opened a middle-phase trial of its dual CCR5/CCR2 inhibitor cenicriviroc (TBR-652).

WHO Issues First Gay and Transgender HIV Prevention Guidelines

The World Health Organization (WHO) for the first time has developed pubic health guidelines for HIV prevention and care focused on men who have sex with men and transgender people. alt