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CROI 2015: HIV Care in New York City [VIDEO]

Timely linkage to HIV care increased to 76% and achievement of viral suppression within a year of starting antiretroviral treatment rose to almost 70% over the past several years in New York City, but there are still notable disparities across population subgroups and more remains to be done, according to a study presented at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) this week in Seattle.

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CROI 2015: HIV Maturation Inhibitor BMS-955176 Looks Promising In Early Study

A second-generation HIV maturation inhibitor, BMS-955176, demonstrated good safety and high potency, including activity against viral strains that were not susceptible to an earlier drug in this class, researchers reported at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) taking place this week in Seattle.

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CROI 2015: PrEP Use Rising in San Francisco, but Scale-Up Could Cut New Infections

Use of Truvada (tenofovir/emtricitabine) pre-exposure prophylaxis, better known as PrEP, is increasing in San Francisco, but it is still only reaching about one-third of people who could benefit, and wider use could reduce new HIV infections by 70%, according to a report at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) this week in Seattle.

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CROI 2015: Week-on, Weekend-Off HIV Treatment Controls Viral Load in Young People

Taking an efavirenz-based antiretroviral regimen during the week and taking no medication on 2 days over the weekend was just as effective as daily treatment at controlling viral load in an 11-country trial of adolescents and young people, Karina Butler from Our Lady’s Children’s Hospital in Dublin reported at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) taking place this week in Seattle.

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CROI 2015: PrEP Stops 86% of HIV Infections in PROUD Study

A study of pre-exposure prophylaxis (PrEP), the English PROUD study, demonstrated the highest effectiveness yet seen for this method of HIV prevention, the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle heard today. The effectiveness was 86%; for every 20 infections that might have occurred in participants, 17 were stopped by PrEP. 

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CROI 2015: Weekends Off Treatment Works Well for Some Young People with HIV [VIDEO]

Taking breaks from antiretroviral therapy on the weekend did not lead to viral rebound or other problems for adolescents and young adults who had prolonged viral suppression on efavirenz-based regimens, according to a presentation at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) this week in Seattle.

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CROI 2015: On-Demand PrEP Prevents 86% of HIV Infections in Ipergay

A French and Canadian study of pre-exposure prophylaxis (PrEP) presented today at the 2015 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle found that the HIV infection rate for participants taking an intermittent PrEP regimen was 86% lower than for people taking an inactive placebo. Extraordinarily, this is exactly the same level of effectiveness that was demonstrated in the English PROUD study, whose outcomes were presented 15 minutes before Ipergay. Ipergay is a very different study than PROUD and it is encouraging that 2 different ways of taking PrEP have both proved effective in gay men, at least in a western European context.

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