HIV and AIDS
Neuropathy

 
PERIPHERAL NEUROPATHY
Condition characterized by sensory loss, pain, muscle weakness, and wasting of muscle in the hands or legs and feet. It may start with burning or tingling sensations or numbness in the toes and fingers. In severe cases, paralysis may result. Peripheral neuropathy may arise from an HIV-related condition or be the side effect of certain drugs, some of the nucleoside analogs in particular.

Incidence Rates and Relative Risks Risk with Hydroxyurea (HU)



Medical Cannabis Relieves Peripheral Neuropathy Pain in People with HIV  2/16/07

Exposure to Stavudine and Didanosine Is Significantly Associated with a Heightened Risk for Symptomatic Sensory Neuropathy - 5/05/06

5% Lidocaine Gel Is Ineffective for Treatment of HIV-associated Distal Symmetric Polyneuropathy - 2/02/05

Tenofovir Approved for First Line Therapy in Adults - 10/29/04

Mitochondrial DNA Levels in Fat and Blood Cells from Patients with Lipodystrophy or Peripheral Neuropathy and the Effect of 90 Days of Treatment with High-dose Coenzyme Q  - 10/22/04

What Is Coenzyme Q?  - 10/22/04

Treatment with Antiretroviral Therapy, Especially Didanosine and Stavudine, Increases Risk of Sensory Neuropathies - 10/20/04
Acetyl-L-carnitine Reverses NRTI-related Nerve Degeneration - 8/11/04

Co-administration of ddI (didanosine) at Standard Doses Plus TDF (tenofovir) Significantly Decreases CD4, CD8 and Total Lymphocyte Counts - 3/19/04

Use of High-concentration Capsaicin Patch Results in Substantial Pain Reduction in HIV Patients with Distal Symmetrical Polyneuropathy (DSPN) 3/08/04