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Few
clinical manifestations have been noted
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Frank
diabetes mellitus is uncommon
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Fasting
glucose levels are generally normal
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Syndrome
is characterized by fasting hyperinsulinemia
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Two-hour
glucose and insulin AUC levels are significantly abnormal following
glucose challenge
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The evaluation and diagnosis of glucose abnormalities in patients
with HIV infection can be challenging, as few clinical manifestations
have been noted. As was mentioned earlier, the presence of frank,
diabetes mellitus is uncommon.
Fasting glucose levels are also generally normal. However,
the most characteristic sign is fasting hyperinsulinemia.
In these patients, 2-hour glucose and insulin area-under-the-curve
(AUC) levels are significantly abnormal following a glucose challenge.
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