Glucose: Evaluation and Diagnosis

Few clinical manifestations have been noted
Frank diabetes mellitus is uncommon
Fasting glucose levels are generally normal
Syndrome is characterized by fasting hyperinsulinemia
Two-hour glucose and insulin AUC levels are significantly abnormal following glucose challenge

• The evaluation and diagnosis of glucose abnormalities in patients with HIV infection can be challenging, as few clinical manifestations have been noted. As was mentioned earlier, the presence of frank, diabetes mellitus is uncommon.

• Fasting glucose levels are also generally normal. However, the most characteristic sign is fasting hyperinsulinemia.

• In these patients, 2-hour glucose and insulin area-under-the-curve (AUC) levels are significantly abnormal following a glucose challenge.


 

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