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Study
of HIV+ patients with either increased truncal fat and/or loss
of facial and extremity fat |
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Compared
to age and BMI-matched subjects from the Framingham Offspring
Study
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Fasting
glucose, insulin, lipid levels, glucose and insulin responses,
and anthropometric measurements were determined
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Hadigan and colleagues have examined the metabolic abnormalities and
cardiovascular disease risk factors in 71 patients with HIV infection
and lipodystrophy.1 These individuals had either increased truncal
fat and/or the loss of facial and extremity fat.
• They were compared with 213 healthy control subjects from the
Framingham Offspring Study. In addition, 30 HIV-infected patients
without fat redistribution were compared separately with 90 matched
control subjects, also from the Framingham Offspring Study.
• The researchers obtained fasting glucose, insulin, lipid levels,
as well as glucose and insulin response to standard oral glucose challenge.
In addition, anthropometric measurements were taken.
Reference:
1. Hadigan C, Meigs JB, Corcoran C et al. Metabolic abnormalities
and cardiovascular disease risk factors in adults with human immunodeficiency
virus infection and lipodystrophy. Clin Infect Dis. 2001;32:130-9.
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