|
Defining
the Syndrome
| •
|
Increased
blood lactate with normal pH |
| •
|
Usually
normal HCO3 |
| •
|
May
be symptomatic or asymptomatic |
|
-
|
Significance
of asymptomatic hyperlactatemia unknown
|
|
-
|
Symptomatic
hyperlactatemia associated with non-specific GI complaints and/or
abnormal LFTs |
| |
•
Patients may also develop hyperlactatemia as a complication of antiretroviral
therapy.
• The syndrome is defined as an increased blood lactate in
the wake of a normal pH. Usually, there is also a normal bicarbonate.
• The mortality is high with this syndrome, exceeding 75%.
|
|
