Updated Perinatal Guidelines from the National Institutes of Health

The Public Health Service Task Force Perinatal treatment guidelines have been revised by the Perinatal HIV Guidelines Working Group. The updated guidelines are entitled “Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV-1 Transmission in the United States."  The revised document contains recommendations on the following:

·         Updated information on nevirapine (Viramune) and hepatic/rash toxicity and recommendations regarding the use of nevirapine-based HAART for prevention of mother-to-child transmission of HIV.

·         Updates to Clinical Scenario #1 regarding the use of efavirenz (Sustiva) and nevirapine during pregnancy and change in efavirenz's FDA Pregnancy Classification (reclassified to Pregnancy Class D—positive evidence of fetal harm).

·         Updates to the abacavir (Ziagen), lamivudine (Epivir), stavudine (Zerit), zidovudine (Retrovir), efavirenz, nevirapine, indinavir (Crixivan), and nelfinavir (Viracept) sections of the "Safety and Toxicity of Individual Antiretroviral Agents in Pregnancy" supplement.

All new information is highlighted in the document.

The updated guidelines document is available in the PERINATAL GUIDELINES section of the GUIDELINES page on the AIDSinfo Web site at http://aidsinfo.nih.gov.

You can download guidelines or you can request to receive the guidelines by e-mail or regular mail on the AIDSinfo Web site.

Your feedback is important!

The Perinatal HIV Guidelines Working Group would like to hear your feedback on the latest revisions to the "Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV-1 Transmission in the United States." Please send your comments with the subject line "Perinatal Comments" to AIDSinfoWebmaster@aidsinfo.nih.gov by March 10, 2005.

02/25/05

Source
http://aidsinfo.nih.gov.

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