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The manufacture and distribution of the HIV protease inhibitor Agenerase (amprenavir) was
discontinued by GlaxoSmithKline (GSK) in October 2007
.
Agenerase has been replaced by the HIV PI Lexiva (fosamprenavir)
, also manufactured by GSK. Fosamprenavir is a pro-drug of amprenavir, which is used for treatment of HIV infection in combination with low-dose ritonavir and other antiretroviral drugs.
Information on the HIV PI Lexiva
.
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Protease Inhibitors
Agenerase
(amprenavir)
Aptivus
(tipranavir)
Crixivan
(indinavir)
Invirase
(saquinavir hard gel)
Kaletra
(lopinavir/ritonavir)
Lexiva
(fosamprenavir)
Norvir
(ritonavir)
Prezista
(darunavir)
Reyataz
(atazanavir)
Viracept
(nelfinavir)
Nucleo
side /
Nucleo
tide
Reverse
Transcriptase Inhibitors
Combivir
(zidovudine/lamivudine)
Epivir
(lamivudine; 3TC)
Emtriva
(emtricitabine; FTC)
Epzicom
(abacavir + lamivudine)
Retrovir
(zidovudine; AZT)
Trizivir
(abacavir + zidovudine +lamivudine)
Truvada
(tenofovir / emtricitabine)
Videx
(didanosine; ddI)
Viread
(tenofovir)
Zerit
(stavudine; d4T)
Ziagen
(abacavir)
non Nucleoside Reverse
Transcriptase Inhibitors
Etravirine
(Intelence; TMC125)
Rescriptor
(delavirdine)
Sustiva
(efavirenz)
Viramune
(nevirapine)
Entry Inhibitors
(including Fusion Inhibitors)
Fuzeon
(enfuvirtide, T-20)
Selzentry
(maraviroc)
Fixed Dose Combinations
Atripla
(efavirenz + emtricitabine + tenofovir)
Combivir
(zidovudine + lamivudine)
Trizivir
(abacavir + zidovudine + lamivudine)
Truvada
(tenofovir + emtricitabine)
Integrase Inhibitor
Isentress
(raltegravir)
Fuzeon
(enfuvirtide,
T-20) Selzentry
(maraviroc)
