Hepatitis B
Conference Coverage
Conference Coverage
FDA-approved HBV Treatments
Baraclude  (entecavir)
Epivir-HBV
   (lamivudine; 3TC)
Intron A   (interferon alfa-2b)
Hepsera   (adefovir dipivoxil)
Pegasys
  (peginterferon alfa-2a)
Tyzeka   
(telbivudine)
Hepatitis C Top News Articlespatitis
Tenofovir May Be More Effective and Less Expensive than Lamivudine (Epivir-HBV) and Adefovir (Hepsera) as First-line Treatment for HBeAg- Chronic Hepatitis B - 5/09/08
Lamivudine (Epivir-HBV) plus Adefovir (Hepsera) Is an Effective Regimen for Lamivudine-resistant HBV Patients Who Develop Resistance to Entecavir (Baraclude) - 5/09/08
Pegylated Interferon plus Ribavirin Is Effective for Patients with HCV-HBV Coinfection - 5/09/08
Entecavir (Baraclude) Produces Greater Decrease in HBV DNA than Adefovir (Hepsera) in Treatment-naive HBeAg+ Patients: 96 Week Data from EARLY Study - 5/06/08
Three Years of Continuous Entecavir (Baraclude) in Chinese Patients with Prior Lamivudine (Epivir-HBV) Failure: Studies ETV-056 and ETV-050 - 5/06/08
Entecavir (Baraclude) Treatment in Japanese Nucleoside-naive Chronic Hepatitis B Patients - 5/06/08
R.E.V.E.A.L.-HBV Study Shows Persistently High Hepatitis B Viral Load Raises the Risk of Liver Cancer - 4/29/08
Tenofovir (Viread) Is Effective in Chronic Hepatitis B Patients with Prior Nucleoside/nucleotide Experience - 4/29/08
European Commission Approves Tenofovir (Viread) for Chronic Hepatitis B - 4/29/08
European Association for the Study of the Liver (EASL) Meeting Opens in Milan - 4/24/08
Pegasys Demonstrates Continued Benefits for Chronic Hepatitis B Patients at 4 Year - 4/24/08
Gilead Announces 72-Week Data from Pivotal Studies of Tenofovir (Viread) for Chronic Hepatitis B - 4/24/08
Lamivudine (Epivir-HBV) Monotherapy versus Lamivudine plus Adefovir (Hepsera) for Chronic Hepatitis  - 4/11/08
Study Looks at Impact of Hepatitis B Disease Progression on Quality of Life - 4/04/08
FDA Grants Orphan Drug Approval of Hepatitis B Immune Globulin to Prevent Post-transplant Recurrence - 4/04/08
Five-year Data Show Continued Low Rate of Resistance to Entecavir (Baraclude) in Chronic Hepatitis B Patients - 3/28/08
Has the Time Come for Expanded Off-label Use of Combination Treatment for Chronic Hepatitis B? - 3/21/08
Tenofovir (Viread) plus Lamivudine (Epivir-HBV) Appears Effective as Rescue Therapy for Cirrhotic Patients with Resistance to Adefovir (Hepsera) - 3/21/08
European Medicines Agency Gives Positive Opinion on Tenofovir (Viread) for Treatment of Chronic Hepatitis B - 3/21/08
Canadian Health Officials Warn against Use of Tebivudine (Tyzeka/Sebivo) in Combination with Interferons - 3/18/08
Occult Hepatitis B Virus in Individuals without Liver Disease - 3/14/08
Vaccination Dramatically Cuts Hepatitis B in Italy, but Concerns Remain - 3/11/08
Hepatitis B: Reflections on the Current Approach to Antiviral Therapy - 3/07/08
Adefovir (Hepsera) for Treatment of Patients with Chronic Hepatitis B Resistant to Lamivudine (Epivir-HBV) - 3/04/08
Likelihood of Adefovir (Hepsera) Resistance in Nucleoside-naive Hepatitis B Patients - 2/29/08
HBeAg and HBV DNA Predict Outcomes of Pegylated Interferon Therapy for Chronic Hepatitis B - 2/19/08
Tenofovir (Viread) Is Effective after Adefovir (Hepsera), but Not Vice Versa - 2/01/08
Lamivudine Prevents HBV Reactivation in Immunosuppressed Patients - 1/29/08
Disease Progression in Patients with HBeAg-negative Chronic Hepatitis B - 1/29/08
Hepatitis B Exacerbation May Occur in Women after Giving Birth - 1/25/08
Overview of the Natural History of Chronic Hepatitis B - 1/18/08
Long-term Response to Lamivudine (Epivir-HBV) in Children with Chronic Hepatitis - 1/18/08
Relation between HBV "X" Gene Integration and Development of Hepatocellular Carcinoma - 1/14/08
Once-daily Clevudine Demonstrates Early HBV Suppression and Biochemical Improvement in Hepatitis B Patients with Liver Cirrhosis - 1/14/08
Extended Duration Pegylated Interferon Alfa-2a (Pegasys) for Patients with HBeAg Negative Chronic Hepatitis B - 1/11/08
HBV Viral Load at Week 4 of Lamivudine (Epivir-HBV) Treatment Predicts Response at 5 Years - 1/08/08
Two Studies Show Telbivudine (Tyzeka) Is Superior to Lamivudine (Epivir-HBV) for Chronic Hepatitis B - 1/08/08
Telbivudine (Tyzeka) Superior to Adefovir (Hepsera) at 52 Weeks - 1/04/08
Clinical Significance of Persistently Normal ALT in Chronic Hepatitis B Patients - 1/04/08
Individuals with Hepatitis B Virus Genotype C Experience HBeAg Clearance Later and Less Often - 12/14/07
Hepatitis Reactivation Following HBeAg Seroconversion - 12/14/07
Entecavir (Baraclude) for Chronic Hepatitis B Provides Continued Benefits through 96 Week - 12/11/07
Resistance to Adefovir (Hepsera) Is Uncommon after 3 Years in Hepatitis B Patients Treated with Adefovir plus Lamivudine (Epivir-HBV) - 12/11/07
Effect of Lamivudine (Epivir-HBV) and Adefovir (Hepsera) in Preventing Hepatocellular Carcinoma - 12/07/07
Impact of Adefovir (Hepsera) on Liver Fibrosis and Histological Activity Assessed Using FibroTest-ActiTest in Hepatitis B Patients - 12/07/07
Liver Stiffness Measurement (FibroScan) More Useful for Assessing Fibrosis in Patients with HCV Compared with HBV - 12/04/07
Chronic Hepatitis B Patients May Have Significant Liver Disease Despite Normal ALT- 12/04/07
Preemptive Lamivudine Therapy Reduces Risk of Liver Disease Flares in Hepatitis B Patients Starting Cancer Chemotherapy - 11/30/07
Pegylated Interferon Alfa-2a (Pegasys) plus Ribavirin for Patients with HBV and HCV Coinfection - 11/30/07
New Data on Telbivudine (Tyzeka) for Treatment of Chronic Hepatitis B - 11/27/07
Decline in Number of Patients Requiring Liver Transplants Due to Hepatitis B - 11/27/07
Digestive Disease Week (DDW) 2008 Online Abstract Submissions Due December 1 - 11/27/07
Predictors and Long-term Outcomes Associated with Hepatitis B Surface Antigen (HBsAg) Clearance - 11/20/07
Chronic Hepatitis B Patients with Low HBV Viral Load Still Have an Elevated Risk of Liver Cancer: R.E.V.E.A.L.-HBV Study - 11/16/07
Gender Difference in the Natural Course of HBeAg-Positive Chronic Hepatitis B - 11/13/07
Tenofovir (Viread) Is Superior to Adefovir (Hepsera) at 48 Weeks for Both HBeAg Positive and HBeAg Negative Patients with Chronic Hepatitis B - 11/09/07
Entecavir (Baraclude) Maintains HBV Suppression through 4 Years in Nucleoside-naive HBeAg Positive Patients - 11/06/07
Hepatitis B Virus DNA Found in 16th Century Mummy in Korea - 11/06/07
12 Weeks of Pegylated Interferon Works as Well as 48 Weeks in Selected Patients with HBeAg Positive Chronic Hepatitis B - 11/03/07
Interferon for the Treatment of Chronic Hepatitis Delta - 10/26/07
Clinical Significance of Persistently Normal ALT in Chronic Hepatitis B Patient - 10/23/07
Specific HBV Mutations Predict Loss of Sensitivity to Lamivudine (Epivir-HBV) - 10/23/07
Hepatitis B Patients Who Spontaneously Clear HBeAg and Achieve Sustained Remission have Reduced Liver Fibrosis Progression - 10/19/07
Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients - 10/16/07
Gilead Sciences Seeks U.S. and European Marketing Approval for Tenofovir (Viread) for Treatment of Chronic Hepatitis B - 10/16/07
HBV Genotype and Baseline Viral Load Predict Response to Adefovir (Hepsera) in Lamivudine-resistant Chronic Hepatitis B Patients - 10/12/07
Pharmasset Starts Two 48-week Phase 3 Registration Studies of Clevudine for Hepatitis B - 10/05/07
Maxygen Announces Hold on Development of MAXY-alpha (R7025) for Treatment of Hepatitis B and C - 9/28/07
Good Hepatitis B Treatment Outcomes in Patients with Advanced Liver Fibrosis or Cirrhosis - 9/14/07
Occult HBV Coinfection Associated with Poorer Response to Hepatitis C Treatment - 9/14/07
Prevention of Variceal Bleeding in Candidates Awaiting Liver Transplantation - 9/11/07
Primary Biliary Cirrhosis Is More Severe in African-American and Hispanic Patients Compared to Caucasians - 9/11/07
HCV and HBV Spreading More Slowly among Injection Drug Users in San Francisco - 9/07/07
Sorafenib (Nexavar) Demonstrates Promising Results for Hepatocellular Carcinoma - 9/07/07
Coffee Consumption May Reduce the Risk of Liver Cancer - 8/31/07
Differences in Response to a Hepatitis B Vaccine Booster among Children and Adolescents Vaccinated during Infancy - 8/28/07
Experimental Hepatitis B Vaccine Aims to Prevent HBV Reinfection after Living Donor Liver Transplantation - 8/28/07
Presence of Mixed Hepatitis B Genotypes Occurs More Frequently in HIV-HBV Coinfected Patients   - 8/17/07
Liver Disease and Survival Outcomes in HIV-HBV Coinfected Individuals   - 8/17/07
Community-based Study in Taiwan Provides More Evidence of Link between Hepatitis C and Type 2 Diabetes   - 8/17/07
Studies Examine Occult HBV Infection in HIV Positive and HIV-HCV Coinfected Patients - 8/14/07
Efficacy and Safety of Boosted Fosamprenavir (Lexiva) versus Lopinavir/ritonavir (Kaletra) in Treatment-naive HIV Patients with Hepatitis B or C Coinfection in the KLEAN Study   - 8/07/07
Sodium Levels Can Help Predict Outcomes before and after Liver Transplantation   - 8/07/07
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EASL 2008 - April 2008 
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FDA-approved
Monotherapies for HBV

Baraclude
  (entecavir)
 Epivir-HBV
  (lamivudine; 3TC)
Intron A
  (interferon alfa-2b)
Hepsera
  (adefovir dipivoxil)
Pegasys
  (peginterferon alfa-2a)
Tyzeka
  (telbivudine)

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