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HCV
Experimental Treatments
Boceprevir
(aka SCH 503034)
GS
9132 and GS 9190
and GS 9450
IDX136,
IDX316, IDX375 and IDX184
Pegylated
Interferon Lambda
PSI-879,
PSI-7851 and
PSI-7977
Vertex,
InterMune, and Idenix Present Hepatitis
C Drug Development Updates at Investor Conference
1/22/2010
Pharmasset
Announces Continuation of Phase 2b Trial of HCV Polymerase
Inhibitor RG7128
12/04/09
Oral HCV
Polymerase Inhibitor RG7128
plus Protease Inhibitor RG7227
(ITMN-191) Suppresses HCV Viral Load without
Interferon or Ribavirin
11/13/09
InterMune and Roche
Begins Trial of Ritonavir-boosted ITMN-191
(RG7227) for Genotype 1 Chronic Hepatitis C Patients
10/06/09
Roche and InterMune Begin
Phase 2b Trial of HCV Protease
Inhibitor RG7227/ITMN-191
9/04/09
Data
on Experimental Anti-HCV Drugs ITMN-191/R7227,
VCH-916, VCH-222, TMC435, ANA598, MK-7009, GS-9450, Abbott/Enanta
and Idenix Agents
5/12/09
New
Hepatitis C Treatment Trials: HCV Polymerase Inhibitor
R7128, Nucleotide
Prodrug IDX184, and Albumin Interferon (Albuferon)
1/20/09
HCV
Polymerase Inhibitor R7128 Demonstrates Good Antiviral
Activity in Genotype 2 or 3 Prior Non-responders and Relapsers
11/14/08
R7128 plus ITMN-191 Perform Well in
Laboratory Study; STAT-C Combination Clinical Trial Now
Underway
11/14/08
Natural
Prevalence of Resistance to HCV
Protease Inhibitors
9/25/08
Combination
Therapy with Investigational HCV Polymerase Inhibitor
R7128 Produces Rapid
Response in Patients with Genotype 2/3 HCV
9/12/08
Pharmasset
Releases Preliminary Data from Phase 1 Study of Investigational
HCV Polymerase Inhibitor R7128
8/08/08
InterMune
and Anadys Begin Phase 1 Clinical Trials of Experimental
HCV Therapies ITMN-191 and
ANA598
6/06/08
R7128 Demonstrates Potent Anti-HCV
Activity in Combination with Pegylated Interferon/Ribavirin;
Ongoing Trial to be Expanded
4/29/08
HCV
Polymerase Inhibitor R1626 Produces Good Response with
Pegylated Interferon/Ribavirin and Has High Barrier to
Resistance
4/29/08
InterMune
Presents Top-line Results from Phase 1b Trial of HCV Protease
Inhibitor ITMN-191
Monotherap
4/04/08
VCH-759,
VCH-916, VCH-222
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