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Kaletra (lopinavir/ritonavir)
Articles on Kaletra Full US Prescribing Inormation Medication Guide www.abbott.com
FDA Warns of Kaletra Toxicity for Premature Infants 3-11-2011 Analysis of clinical outcomes in African American HIV-1 positive patients receiving lopinavir/ritonavir in a large urban AIDS clinic 8-17-2010 Clinical outcomes, immmunologic function and virologic suppression among HIV infected children receiving Lopinavir/ritonavir-based second line antiretroviral therapy at National Pediatric Hospital, Phnom Penh, Cambodia 8-17-2010 Comparison of total and unbound lopinavir (LPV) pharmacokinetics (PK) in HIV-infected pregnant women receiving lopinavir/ritonavir (LPV/r) soft-gel capsules (SGC) or tablets 8-17-2010 Antiretroviral monotherapy with ritonavir-boosted lopinavir or fosamprenavir in HIV-cirrhotic patients is a safe, effective and costs-saving strategy 8-17-2010 Lopinavir/ritonavir combined with raltegravir demonstrated similar antiviral efficacy and safety as lopinavir/ritonavir combined with tenofovir disoproxil fumarate/emtricitabine in treatment-naïve HIV-1 infected subjects 8-17-2010 Baseline HIV-1 RNA does not affect virologic response to lopinavir/ritonavir-based regimens in antiretroviral-naive subjects: results of a 96-week meta-analysis of >2400 subjects 8-17-2010 Market shift towards heat-stable lopinavir/ritonavir demonstrates the need for improved formulations for second line treatment of HIV/AIDS in low- and middle-income countries 8-17-2010 The effect of lopinavir/r monotherapy on viral load and on the selection of resistance-associated mutations in seminal plasma 8-17-2010 Incidence of emtricitabine, tenofovir, raltegravir, and lopinavir resistance following twice-daily (BID) lopinavir/ritonavir (LPV/r) in combination with once-daily (QD) emtricitabine/tenofovir (FTC/TDF) or twice daily raltegravir (RAL) in antiretroviral-naïve, HIV-1 infected subjects: 48-week results of a 96-week randomized trial (study M10-336) 8-17-2010 The effect of lopinavir/ritonavir on the pharmacokinetics of TMC207, an investigational antimycobacterial agent 8-17-2010 Real-life safety and efficacy of lopinavir/ritonavir (LPV/r) in drug-naive and antiretroviral (ARV) treatment-experienced HIV patients: 96-week follow-up 8-17-2010 NRTI-sparing Regimen of Lopinavir/ritonavir plus Raltegravir Works as Well as Traditional 3-drug HAART 7-23-2010 Switching from Kivexa [ABC/3TC ]+Kaletra [LPV/r] to Truvada [TDF/FTC]+Kaletra [LPV/r] Reduces High Cholesterol: Results of a 12 Week Randomized, Controlled Study (ROCKET II) 7-23-2010 NRTI-sparing Regimen of Lopinavir/ritonavir plus Raltegravir Works as Well as Traditional 3-drug HAART 7-23-2010 Suboptimal Adherence Has Less Effect on Boosted Darunavir (Prezista) than Lopinavir/ritonavir (Kaletra) 7-02-2010 FDA Approves Once-daily Lopinavir/ritonavir (Kaletra) for Certain Treatment-experienced HIV Patients 4-30-2010 FDA Announces Label Changes for Darunavir (Prezista), Didanosine (Videx), and Lopinavir/ritonavir (Kaletra) 2-02-2010 Raltegravir (Isentress) Activity Is Durable at 96 Weeks; Switch from Lopinavir/ritonavir Results in More Viral Breakthrough but Better Lipid Profiles 1-26-2010 Tenofovir/emtricitabine (Truvada) plus Lopinavir/ritonavir (Kaletra) or Raltegravir (Isentress) Work Well for Post-exposure Prophylaxis 9-11-2009 At 96 Weeks, Epzicom and Truvada Demonstrate Comparable Efficacy, Safety, and Tolerability when Combined with Lopinavir/ritonavir (Kaletra) 8-4-2009 Once-daily Lopinavir/ritonavir (Kaletra) Works as Well as Twice-daily dosing in Treatment-naive HIV Patients 7-31-2009 Switching from Lopinavir/ritonavir (Kaletra) to Boosted Atazanavir (Reyataz) Reduces Visceral Fat and Improves Glucose Metabolism 7-10-2009 Protease Inhibitor Monotherapy using Lopinavir/ritonavir (Kaletra) or Boosted Atazanavir (Reyataz) Maintains Viral Suppression 6-19-2009 How Effective Are Boosted Dual Protease Inhibitor Regimens with No Additional Drugs in Treatment-naive HIV Patients? 5/22/09 First-line Therapy with Zidovudine/lamivudine plus Lopinavir/ritonavir Leads to Greater Bone Loss than Nevirapine plus Lopinavir/ritonavir 5/19/09 Lopinavir/ritonavir (Kaletra) Is Superior to Nevirapine (Viramune) for HIV-infected Children Who Received Single-dose Nevirapine at Birth 5/15/09 Raltegravir (Isentress) plus Lopinavir/ritonavir (Kaletra) Produces Rapid Viral Load Decline in Treatment-naive HIV Patients 5/08/09 Raltegravir (Isentress) plus Lopinavir/ritonavir (Kaletra) Produces More Rapid HIV Decline in Treatment-naive HIV Patients 4/10/09 Lopinavir/ritonavir (Kaletra) Label Changed to Reflect Potential Risk of Heart Rhythm Abnormalities 4/10/09 Lopinavir/ritonavir (Kaletra) Monotherapy May Be Hazardous for Patients with a History of Low CD4 Cell Counts 3/03/09 Switching from Lopinavir/ritonavir (Kaletra) to Raltegravir (Isentress) Leads to Poorer HIV Suppression, but Better Lipid Profiles: SWITCHMRK 2/17/09 Factors affecting virologic response to darunavir/ritonavir and lopinavir/ritonavir in treatment-naïve HIV-1-infected patients in ARTEMIS at 96 weeks 2/17/09 Single Agent Therapy with Lopinavir/Ritonavir Suppresses HIV-1 Viral Replication in ARV Naïve Patients: IMANI II - 96 Week Final Results 11/05/2008
Three-year Efficacy of Lopinavir/ritonavir Monotherapy in the OK04 Trial 11/05/2008 Time to Virological Failure with Boosted Atazanavir (Reyataz) or Lopinavir/ritonavir (Kaletra) Is Not Affected by Use of H2 Receptor Blockers 9/12/2008 Effect of Lopinavir/ritonavir (Kaletra) Monotherapy on Symptoms and Quality of Life 9/12/2008 No Increased Risk of Birth Defects with Prenatal Lopinavir/ritonavir (Kaletra) Exposure 8/22/08 Time to Virological Failure with Boosted Atazanavir (Reyataz) or Lopinavir/ritonavir (Kaletra) Is Not Affected by Use of H2 Receptor Blockers 9/12/2008 Boosted Atazanavir and Lopinavir/ritonavir (Kaletra) Have Similar Efficacy, but Side Effects Differ across Racial/ethnic Groups 8/12/08 Lopinavir/ritonavir (Kaletra) Tablet Dosed Once-Daily or Twice-Daily Confers Similar Clinical Results across Racial/ethnic Lines 8/12/08 Trough Lopinavir Concentrations <1 ƒÊg/mL Are Not Associated with Virologic Failure in Antiretroviral-Naive Patients Receiving a Lopinavir/ritonavir-Based 3-Drug Regimen 8/10/08 Impact of Gender on Response to Lopinavir/ritonavir (LPV/r) Tablets Dosed QD or BID Administered with Tenofovir Disoproxil Fumarate (TDF) and Emtricitabine (FTC) in Antiretroviral-naïve (ARV) Subjects: Results from Study M05-730 8/10/08 Comparable HIV-1 Viral Suppression and Immunologic Recovery of White and Non-White Antiretroviral-Naïve Subjects Taking Lopinavir/ritonavir (LPV/r) Tablets + Tenofovir Disoproxil Fumarate (TDF) and Emtricitabine (FTC) through 48 Weeks 8/10/08 Week-96 End of Trial Analysis of Antiretroviral-naïve Patients Randomized to the Lopinavir/ritonavir Single Drug Arm in the MONARK Trial 8/10/08 Predictors of Persistence with Lopinavir/ritonavir (LPV/r) Soft-Gelatin Capsule-Based Antiretroviral Regimens 8/10/08 Health-Related Quality of Life (HRQoL) Improvement in Antiretroviral (ARV) Naïve HIV-infected Patients on Atazanavir or Lopinavir With Ritonavir Regimens: Week 24 Results From the CASTLE Study 8/10/08 Efficacy and Safety By Racial Group in ARV-Naïve Subjects Treated With Atazanavir/Ritonavir or Lopinavir/Ritonavir: 48-Week Results for the CASTLE Study (AI424138) 8/10/08 Health-Related Quality of Life (HRQoL) Improvement in Antiretroviral (ARV) Naïve HIV-infected Patients on Atazanavir or Lopinavir with Ritonavir Regimens: Week 24 Results From the CASTLE Study 8/10/08 Epzicom QD vs Truvada QD, Both with Kaletra QD, in ART-Naïve Patients: The HEAT Study 96 Weeks Analysis Results 8/10/08