Publishes Updated Guidelines for Prevention and Treatment of Opportunistic Infections
Ronald Baker, PhD
revised recommendations cover 23 opportunistic infections (both classic AIDS-defining
OIs and other infections commonly seen in children with HIV), with information
on primary prevention, treatment, and maintenance therapy. |
guidelines feature an emphasis on the importance of effective antiretroviral therapy
(ART) to improve immune function in children, information on the diagnosis and
management of immune
reconstitution inflammatory syndrome (IRIS), potential drug interactions,
new guidance on prevention of Pneumocystis
pneumonia in infants, and updated immunization recommendations for hepatitis
papillomavirus (HPV), meningococcal disease, and rotavirus.
"The guidelines will help health care workers and public health officials
who work with children to save lives that might otherwise be lost," said
Kathleen Sebelius, Secretary of the U.S. Department of Health and Human Services.
"The infections that can accompany HIV are often the major cause of illness
and death of HIV-infected children."
hope that doctors and clinicians make use of these new guidelines to ensure that
adolescents with HIV are not severely impacted by other infections," said
Kenneth Dominguez, MD, a coauthor of the new guidelines and epidemiologist at
CDC's Division of HIV/AIDS Prevention. "Despite our country's strong success
in preventing perinatally HIV-infected infants, we must protect the significant
numbers of current HIV-infected children and adolescents who are able to live
longer, healthier lives due to advances in HIV therapy."
text of updated guidelines
NIH, HIV Medicine Association of the Infectious Diseases Society of America, Pediatric
Infectious Diseases Society, and American Academy of Pediatrics. Guidelines
for the Prevention and Treatment of Opportunistic Infections among HIV-exposed
and HIV-infected Children. Morbidity and Mortality Weekly Report 58:
1-166. August 26, 2009 (early release); September 4, 2009 (print edition).
NIH News. U.S. Updates Clinical Guidelines for Prevention and Treatment
of Opportunistic Infections among HIV-Exposed and HIV-Infected Children. August