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Pegasys (peginterferon alfa-2a)

In 2005, the US Food and Drug Administration (FDA) approved PEGASYS for the treatment of chronic hepatitis B. Already the most prescribed hepatitis C medication in the United States, PEGASYS is the first and only pegylated interferon approved for the treatment of chronic hepatitis B, including both main types of the virus.

PEGASYS helps in two important ways:

- PEGASYS slows replication of the hepatitis B virus.
- PEGASYS boosts the body's immune system.

Pegasys Product Information
(Pegasys for treatment of Hepatitis B starts on page 25 of PDF)

HBV Pegasys Roche Web Page


Articles on Pegasys (peginterferon alfa-2a) for Treatment of Hepatitis B


Review Finds Pegylated Interferon Is More Effective than Lamivudine for Chronic Hepatitis B, but Study Shows Little Activity against HBV Genotype D
11/17/09

Early HBsAg Decline Predicts Sustained Response to Pegylated Interferon; Extended Treatment Can Improve Outcomes
11/17/09

Sustained Response in HBeAg Negative Chronic Hepatitis B Patients 3 Years After Treatment with Pegasys
8/18/09

Pegylated Interferon Monotherapy for Treatment of Chronic Hepatitis B
4/07/09

Sustained HBeAg and HBsAg Loss in Chronic Hepatitis B Patients Treated with Pegylated Interferon
9/26/08

Pegylated Interferon Alfa-2a (Pegasys) Continues to Suppress HBV, but Adding Adefovir (Hepsera) Provides No Extra Benefit in PEG for B Trial
6/03/08


Response to Pegylated Interferon in Adolescents with Chronic Hepatitis B
5/23/08

HBeAg and HBV DNA Predict Outcomes of Pegylated Interferon Therapy for Chronic Hepatitis B
2/19/08

Extended Duration Pegylated Interferon Alfa-2a (Pegasys) for Patients with HBeAg Negative Chronic Hepatitis B
1/11/08

Pegylated Interferon Alfa-2a (Pegasys) plus Ribavirin for Patients with HBV and HCV Coinfection
11/30/07

12 Weeks of Pegylated Interferon Works as Well as 48 Weeks in Selected Patients with HBeAg Positive Chronic Hepatitis B
11/03/07

Pegasys Suppresses HBV DNA More Than Lamivudine Over 3 Years
5/04/07

Pegylated Interferon plus Ribavirin in Patients with HBV-HCV Dual Infection
4/27/07

Peginterferon Alfa-2a (Pegasys) plus Adefovir Is Safe and Results in Greater Reduction in ALT and HBV DNA Suppression than Pegasys Alone
- 4/27/07