Back HIV/Hepatitis Coinfection

Coinfection

Hepatitis C Treatment Adherence Is Important for HIV/HCV Coinfected People

Near-perfect adherence to pegylated interferon plus ribavirin offers the best chance of sustained virological response -- or a cure -- for HIV positive people coinfected with hepatitis C virus (HCV), according to a U.S. veterans study described in the August 21, 2012, advance online edition of AIDS and Behavior.

alt

Read more:

Tenofovir Leads to HBsAg Clearance in 8% of HIV/HBV Coinfected Patients

Treatment with tenofovir (Viread) led to hepatitis B surface antigen (HBsAg) clearance -- considered the closest outcome to a cure -- in 8% of HIV positive patients with chronic hepatitis B virus (HBV) coinfection, and in a subgroup clearance was associated with CD4 T-cell count, Dutch researchers reported in the September 15, 2012, Journal of Infectious Diseases.

Read more:

AIDS 2012: Rapid Liver Disease in HIV+ Men with Acute HCV: The Debate Continues

Gay and bisexual men who are already HIV positive when they become infected with hepatitis C virus (HCV) may experience unusually rapid and severe liver disease progression, according to a presentation by Daniel Fierer at the XIX International AIDS Conference (AIDS 2012) last month in Washington, DC. Other experts, however, disagree with this conclusion.

alt

Read more:

ICAAC 2012: Raltegravir Shows Long-term Safety and Efficacy for HIV/HCV and HIV/HBV Coinfection

The HIV integrase inhibitor raltegravir (Isentress) was well-tolerated and demonstrated continued effectiveness for 5 years in treatment-naive and 3 years in treatment-experienced HIV patients coinfected with hepatitis B or C, according to a poster presentation at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) last week in San Francisco.alt

Read more:

AIDS 2012: Is Sexually Transmitted Hepatitis C among HIV+ Gay Men Leveling Off in Amsterdam?

The decade-long outbreak of sexually transmitted hepatitis C virus (HCV) infection among HIV positive men who have sex with men in Amsterdam appears to have leveled off since 2007, perhaps due to increased testing and treatment, but more education and screening are needed, researchers reported at the XIX International AIDS Conference (AIDS 2012) last week in Washington, DC alt

Read more:

AIDS 2012: Triple Infection with HBV Promotes HCV Clearance in People with HIV

altCompetition between hepatitis B virus (HBV) and hepatitis C virus (HCV) in HIV positive people with triple infection appears to promote spontaneous HCV clearance, but lower CD4 T-cell counts and greater liver inflammation reduce the likelihood of clearance, Chinese researchers reported at the XIX International AIDS Conference (AIDS 2012) last month in Washington, DC.

Read more:

AIDS 2012: HIV/HCV Coinfected People at Greater Risk for Liver Decompensation

Despite effective antiretroviral therapy (ART), people coinfected with HIV and hepatitis C remain at higher risk for decompensated liver disease and other liver-related complications than those with hepatitis C alone, according to findings presented this week at the XIX International AIDS Conference (AIDS 2012) in Washington, DC.

Read more:

AIDS 2012: HIV/HBV Coinfection Linked to Higher Mortality, More ART Liver Toxicity

Approximately 6% of people with HIV receiving antiretroviral treatment in Tanzania were coinfected with hepatitis B virus (HBV), which was associated with an elevated risk of death, smaller CD4 T-cell gains, and greater likelihood of liver toxicity, researchers reported at the recent XIX International AIDS Conference (AIDS 2012) in Washington, DC.

Read more:

Hepatitis B Linked to More HIV+ Deaths than Hepatitis C, Risk High for People with AIDS

HIV positive men who are coinfected with hepatitis B virus (HBV) are more likely to die than those with hepatitis C virus (HCV) coinfection, according to research published in the April 20, 2012, advance online edition of Clinical Infectious Diseases. A related study, however, found that liver-related mortality was quite high for HIV/HCV coinfected people with a diagnosis of AIDS.alt

Read more: