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HIV Drug Therapy: Efavirenz Not Linked to Higher Suicide Risk in D:A:D Cohort

People taking antiretroviral therapy (ART) regimens containing the NNRTI efavirenz (Sustiva) were not more likely to die due to suicide or psychiatric illness than those taking other drugs in the large D:A:D cohort, researchers reported last month at the HIV Drug Therapy 2014 meeting in Glasgow.

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HIV in the UK: 76% Diagnosed, 90% on Treatment, 90% Undetectable

The United Kingdom's annual epidemiological report, released in late November, shows that the country already provides HIV treatment to 90% of people accessing clinical services and that 90% of those on treatment have an undetectable viral load. But the country has a long way to go in ensuring that people with HIV are aware of their HIV status -- only 76% of people living with HIV have been diagnosed. The problem is particularly acute in black African communities, as only 62% of African heterosexual men and 69% of African heterosexual women living with HIV have been diagnosed.

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December 1 Is World AIDS Day

Monday, December 1, is the 26th World AIDS Day, an opportunity both to remember the millions of people who have been lost to the epidemic and to raise awareness and focus efforts on ongoing challenges such as gaps in HIV prevention and care. An estimated 1.2 million people in the U.S. and 35 million worldwide are now living with HIV/AIDS, according to the CDC.

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European Commission Approves Boosted Darunavir Combo Rezolsta for HIV

The European Commission last month approved a new fixed-dose coformulation -- dubbed Rezolsta -- containing the HIV protease inhibitor darunavir boosted with the novel pharmacoenhancer cobicistat, Janssen recently announced. The combination is currently being evaluated for U.S. approval.

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HIV R4P: Positive Response to Gift Tokens for Undetectable Viral Load Trial

A U.S. study presented at last month’s HIV Research for Prevention conference found generally positive responses among people with HIV and clinic staff to a trial that used $70 gift tokens as an incentive for people to maintain an undetectable viral load. However, the study found that only just under half of patients had an accurate understanding of what viral load was, and that this did not improve during the study.

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Only 30% of People with HIV in U.S. Have Undetectable Viral Load

Less than one-third of people living with HIV in the U.S. are on antiretroviral therapy (ART) with full viral suppression, which is key to good health and reduced risk of transmission, according to the latest CDC Vital Signs report. In 2011, out of an estimated 1.2 million people living with HIV, just 4 in 10 were receiving HIV medical care and only 3 in 10 had undetectable viral load. "The bottom line is HIV care and treatment not only work to improve health and prolong lives, but also prevent transmission," said CDC director Tom Frieden. "You can save your life and save the life of someone else."

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Delaying Treatment More than 12 Months after HIV Infection Reduces CD4 Cell Recovery

People with HIV who start antiretroviral therapy (ART) more than a year after seroconversion have a lower likelihood of regaining normal CD4 T-cell counts, researchers reported in the November 24 online edition of JAMA Internal Medicine. "If full restoration of immunologic and clinical health is our goal, then the present study tells us that the best chance we have is to start antiretroviral therapy within 12 months of infection," according to an accompanying editorial.

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