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ICAAC: HPV Testing and Pap Smears Identify Anal Cancer Risk in HIV+ Men

Human papillomavirus (HPV) testing and anal Pap testing can detect abnormal cell changes that could progress to anal cancer in HIV positive gay men at an earlier and more treatable stage, and is likely to be cost-effective, according to a study presented at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2011) this month in Chicago. 

Researchers Develop HPV Protein Inhibitor

Researchers constructed a recombinant protein that interferes with the human papillomavirus (HPV) E2 protein, inhibiting viral replication and its ability to cause cancer.

Two HPV Vaccine Doses May Protect as Well as Three

The bivalent Cervarix human papillomavirus (HPV) vaccine may protect against cervical cancer with 2 doses, which would reduce inconvenience and cost compared with the current standard 3-dose regimen, according to study findings described in the September 9, 2011, advance online edition of the Journal of the National Cancer Institute.

FDA Approves New Human Papillomavirus Test

The FDA this week approved Roche's new human papillomavirus test, which identifies genotypes of cancer-causing HPV types 16 and 18, as well as detecting 12 other high-risk types.

Cervarix Vaccine Protects Women against HPV that Causes Anal Cancer

The Cervarix human papillomavirus (HPV) vaccine reduced anal infection with cancer-causing HPV types 16 and 18 in a study of women in Costa Rica, according to a report in the September 2011 issue of The Lancet Oncology.

Anal Pap Screening of HIV+ Men Reveals Half Have Abnormal Cells

More than 80% of HIV positive men agreed to undergo Pap screening for anal cancer, demonstrating its feasibility, and 53% showed signs of potentially pre-cancerous abnormal cell growth.

HPV Vaccine Reduces Cervical Abnormalities

Vaccination of young women in Australia against human papillomavirus (HPV) lowered incidence of serious cervical cell abnormalities and early cervical cancer by nearly 40%.

CROI: HPV and Anal Cancer Research at CROI 2011

Human papillomavirus (HPV) infection remains common among people with HIV and anal cancer is still potentially deadly, researchers reported at CROI 2011.

Lopinavir Fights HPV in Cervical Cancer Cells

The HIV protease inhibitor lopinavir (the main drug in Kaletra) blocked viral proteasome activitation and selectively killed pre-cancerous cervical cells infected with human papillomavirus (HPV).

As reported in the May 3, 2011, advance online edition of Antiviral Therapy, Gavin Batman and Ian Hampson from the University of Manchester in the U.K. and colleagues tested lopinavir in HPV-infected SiHa cervical carcinoma cells in a laboratory study.

Gardasil HPV Vaccine Approved for Anal Cancer

On December 22, 2010, the U.S. Food and Drug Administration (FDA) approved the use of Merck's quadrivalent human papillomavirus (HPV) vaccine, Gardasil, for prevention of anal cancer in men and women age 9-26 years. The vaccine -- which targets high-risk HPV types 6, 11, 16, and 18 -- was previously approved for prevention of cervical cancer in young women.