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March 24 Is World TB Day

Monday, March 24, is World TB Day, an opportunity to raise awareness about tuberculosis and the need for expanded testing and treatment worldwide. TB remains a threat in high-income countries including the U.S. as well as in resource-limited settings, and it is a major cause of death among people with HIV. The Stop TB Partnership estimates that 9 million people worldwide get sick with TB annually, but 3 million of them do not get the care they need.

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CROI 2014: New Drugs, Novel Combos Top Tuberculosis News at Conference

Replacing 2 drugs in standard tuberculosis (TB) regimens may shorten therapy and experimental drugs look good in early studies, but a promising diagnostic test did not lead to improvements in mortality, researchers reported at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this month in Boston.

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New Anti-TB Strategy Target: Elimination of the Disease

A major shift in the global anti-tuberculosis (TB) strategy was announced at the Stop TB Symposium just prior to the 44th Union World Conference on Lung Health this month in Paris. Instead of setting modest targets for incremental improvements in TB control, which has been the norm for the past few decades, the TB community -- clearly driven by TB/HIV activism -- is now calling for a global effort to eliminate the ancient disease. 

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Mass Screening, Prevention Did Not Improve TB Control in South African Trial

Widespread screening for tuberculosis, treatment of people with active disease, and providing everyone with preventive isoniazid did not significantly improve tuberculosis (TB) control in a study of workers in South African gold mines, researchers reported in the January 23, 2014, New England Journal of Medicine.

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Preventive Antibiotics for Tuberculosis Lower Risk of Death for People with HIV

Increased screening for tuberculosis (TB) and prophylactic treatment with isoniazid significantly reduced the incidence of active TB disease as well as mortality among patients treated at HIV clinics in Brazil, according to a study published in the August 14, 2013, advance edition of Lancet Infectious Diseases. This is the first evidence that a community-wide effort can prevent people coinfected with HIV and TB from developing active TB disease.

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