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CROI 2017: Prednisone Reduces Risk of Developing TB-IRIS after Starting Antiretroviral Treatment

Prednisone reduces the risk of immune restoration inflammatory syndrome (IRIS) in people with HIV after starting tuberculosis (TB) treatment, a randomized trial called PredART has found. The results were presented last month at the Conference on Retroviruses and Opportunistic Infections in Seattle by Graeme Meintjes from the University of Cape Town in South Africa.

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CROI 2017: Isoniazid Preventive Therapy for TB Reduces Risk of Death for People Living with HIV

A 6-month course of isoniazid preventive treatment (IPT) for at the beginning of the Temprano trial in Ivory Coast reduced the risk of death by 37% over a mean follow-up period of 4.5 years, Anani Badje reported at the Conference on Retroviruses and Opportunistic Infections this month in Seattle.

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AIDS 2016: Neglect of Infectious Disease in Prisons Highlighted at Conference

A special issue of The Lancet was published to coincide with the recent 21st International AIDS Conference in Durban, containing a comprehensive seriesof reviews on the burden of HIV, hepatitis B, hepatitis C, and tuberculosis (TB) among prisoners worldwide.

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CROI 2017: Triple Tuberculosis Regimen Beats XDR-TB in First Trial

A regimen of three oral drugs given for 6 months was enough to clear extensively drug-resistant tuberculosis (XDR-TB) in 29 of the first 31 people to have completed the treatment course, Francesca Conradie of Sizwe Tropical Disease Hospital in Johannesburg reported at the 2017 Conference on Retroviruses and Opportunistic Infections last week in Seattle. If the results are replicated in a larger population, the findings could revolutionize the prospects for treating not just XDR-TB, but also more severe cases of multidrug-resistant tuberculosis (MDR-TB).

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AIDS 2016: New WHO Algorithm Aims to Prevent TB Deaths in People with Advanced HIV

The World Health Organization (WHO) has released a new diagnostic algorithm to reduce the likelihood of seriously ill people with HIV dying of undiagnosed and untreated tuberculosis (TB). The algorithm was presented at a scientific workshop at the 21st International AIDS Conference last month in Durban.

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