Hepatitis B

Coverage of the 2016 AASLD Liver Meeting

HIVandHepatitis.com coverage of the 2016 Liver Meeting, annual conference of the American Association for the Study of Liver Diseases, AASLD), November 11-15, 2016, in Boston.

Hepatitis C

• Glecaprevir/Pibrentasvir Effective for Hepatitis C Patients with Severe Kidney Disease
• Curing Hepatitis C May Help Reduce Kidney Disease Progression
• Real-World Studies Show 8 Weeks of Sofosbuvir/Ledipasvir Equals 12 Weeks for Many Patients
• Generic Sofosbuvir Underperforms in Real World, May Be Due to Suboptimal Regimens
• 6 Weeks of Sofosbuvir/Ledipasvir Cures Genotype 1 Acute Hepatitis C
• Non-Adherence Is Most Important Risk Factor for Sofosbuvir/Ledipasvir Failure
• Primary Care Providers Can Effectively Treat Patients with Hepatitis C
• Grazoprevir Triple Regimen Demonstrates High Cure Rates, Even for Hard-to-Treat Patients
• 8-Week Triple Combo Cures Most Patients with Genotype 1-6 Hepatitis C
• AbbVie Pangenotypic Combination Cures 98% or More Across HCV Genotypes
• AbbVie Pangenotypic Combination Cures Almost All Hard-to-Treat People with HCV Genotype 3
• U.S. Veterans Health System and Australia Show Potential for Rapid Elimination of Hepatitis C
• Real-World Responses to HCV Treatment Among U.S. Veterans Match Stellar Clinical Trial Results
• Grazoprevir/Elbasvir + Sofosbuvir Highly Effective for Hard-to-Treat Genotype 3 Hepatitis C Patients
• Birth Cohort Screening and Linkage to Hepatitis C Care Still Weak in U.S.

HIV/HCV Coinfection

• Hepatitis C Virus Infection Rising Among Gay Men in San Diego
• Sofosbuvir/Ledipasvir Effective for HIV/HCV Coinfected People in Real-World Cohorts
• HIV/HCV Coinfected People See Good Cure Rates in Real-World Clinical Practice in Madrid

Liver Disease Progression

• Liver Cirrhosis and Decompensation on the Rise Among People with Hepatitis C
• Curing Hepatitis C Reduces Liver-Related Complications and Death
• Is DAA Treatment for Hepatitis C Reducing the Need for Liver Transplants?
• Portal Hypertension Less Likely to Improve After HCV Treatment When Fibrosis Is Severe
• Liver Cancer Risk Reduced After Hepatitis C Treatment, But Vigilance Needed

Hepatitis B and D

• Is Better Treatment Improving Outcomes Among People with Hepatitis B?
• Lonafarnib Lowers Hepatitis Delta Levels with Acceptable Side Effects
• GS-4774 Therapeutic Vaccine Shows Little Efficacy in People with Hepatitis B
• Nucleic Acid Polymers Reduce HBsAg Levels and Improve Control of Hepatitis B Virus
• Tenofovir Alafenamide Approved for Hepatitis B, Works Well with Less Effect on Bones

Other Liver Disease

• Nivolumab Shows Good Safety and Promising Response Rates in Liver Cancer Study
• When You Eat May Contribute to Fatty Liver Disease as Much as What You Eat