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ICAAC 2014: Delafloxacin Shows Promise as a Single-dose Treatment for Gonorrhea

A new antibiotic, delafloxacin, demonstrated potent activity against gonorrhea -- including drug-resistant strains -- in a laboratory study, and its pharmacokinetics suggest that single-dose oral treatment will be feasible, according to research presented at the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy this week in Washington, DC.

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STD Prevention Conference: Drug-resistant Gonorrhea Rates Plummet in U.S.

Preliminary results announced at the U.S. 2014 STD Prevention Conference last week in Atlanta have shown that the proportion of cases of gonorrhea that are drug-resistant has fallen since 2011, with a sharp decline between 2012 and 2013. The fall is particularly marked among gay and other men who have sex with men (MSM), who had had the highest rates of drug-resistant gonorrhea.
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Gonorrhea May Become Untreatable Due to Resistance, Experts Warn

Neisseria gonorrhoeae,the bacteria that cause gonorrhea, are becoming increasingly resistant to existing drugs and more difficult to treat in the U.S., public health experts warn in the February 9, 2012, New England Journal of Medicine.

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New Antibiotic Regimens Shown Effective Against Drug-resistant Gonorrhea

A pair of antibiotic regimens using the existing drugs gentamicin or gemifloxacin plus azithromycin work against resistant gonorrhea, but come with side effects, CDC and NIH researchers reported at the 20th Meeting of the International Society for Sexually Transmitted Diseases Research this week in Vienna.

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STD Report Shows Small Rise Overall, Higher Rates for People of Color, Young Gay Men

Reported cases of gonorrhea rose slightly and syphilis declined somewhat during 2010, but the syphilis rate among young black men has increased dramatically over the past 5 years, largely driven by increases among men who have sex with men (MSM), according to the latest sexually transmitted disease (STD) surveillance report from the Centers for Disease Control and Prevention (CDC).alt

Drug Resistant Gonorrhea Makes its Way into North America

The first documented failure of oral treatment for gonorrhea in North America has been reported in Toronto. The article, Neisseria gonorrhoeae Treatment Failure and Susceptibility to Cefexime in Toronto, Canada, published in the January 9, 2013, Journal of the American Medical Association, provides support for growing concern surrounding the second most prevalent bacterial sexually transmitted infection in the world.
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Sexual Partners Should Get Expedited Treatment for Chlamydia and Gonorrhea

Male sexual partners of women diagnosed with chlamydia or gonorrhea should be prescribed antibiotics in an effort to prevent passing infections back and forth, according to new guidelines from the American College of Obstetricians and Gynecologists (ACOG).alt

CDC Recommendation: Dual Treatment to Curb Tide of Drug-Resistant Gonorrhea

Increasing fears about the emergence of antibiotic resistant gonorrhea in the U.S. have prompted new treatment and surveillance recommendations from the Centers for Disease Control and Prevention (CDC). Gail Bolan, director of the agency's Division of STD Prevention, called the move "a critical pre-emptive strike to preserve the last effective treatment option." alt

CDC Warns of Resistant Gonorrhea; First 'Superbug' Found

A week after a CDC report warning that gonorrhea appears to be developing resistance to the last remaining class of effective antibiotics, researchers detected the first extensively resistant strain in Japan. alt

WHO Warns of Global Threat of Drug-resistant Gonorrhea

Multidrug-resistant gonorrhea is a growing concern worldwide and millions of people may be at risk of running out of treatment options unless urgent action is taken, according to an alert issued this week by the World Health Organization (WHO).alt