Hepatitis B
Investigational 2-Dose Dynavax Heplisav Hepatitis B Vaccine May Work Better than Standard 3-Dose Energix-B Vaccine
- Details
- Category: Experimental HBV Drugs
- Published on Tuesday, 12 May 2009 13:47
- Written by HIVandHepatitis.com
An investigational hepatitis B virus (HBV) vaccine may offer the same degree of protection with 2 doses as the standard Engerix-B vaccine does with 3 doses, according to a study presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009) last month in Copenhagen.
Addition of Emtricitabine (Emtriva) Does Not Improve Response to Tenofovir (Viread) for Chronic Hepatitis B
- Details
- Category: HBV Treatment
- Published on Tuesday, 05 May 2009 13:47
- Written by Liz Highleyman
As described in a poster presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009) last month in Copenhagen, T. Berg and an international team of colleagues conducted Study 106, comparing the efficacy of tenofovir/emtricitabine combination therapy versus tenofovir alone for the treatment of chronic hepatitis B.
Adding Ribavirin Does Not Improve Response to Pegylated Interferon Therapy for Chronic Hepatitis B
- Details
- Category: HBV Treatment
- Published on Friday, 14 November 2008 12:49
- Written by Liz Highleyman
In a poster presented at the 59th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2008) last week in San Francisco, researchers reported results from a study assessing whether addition of ribavirin improves response in hepatitis B patients.
Some Individuals Harbor HBV with Adefovir and Tenofovir Resistance Mutations before They Ever Receive Treatment
- Details
- Category: HBV Treatment
- Published on Friday, 17 April 2009 13:49
- Written by HIVandHepatitis.com
Several nucleoside/nucleotide drugs have potent activity against hepatitis B virus (HBV), but the virus can rapidly develop resistance, presenting a barrier to long-term treatment success.
Two Studies Look at Promising Therapies for Liver Cancer: Sorafenib and Doxorubicin
- Details
- Category: Liver Cancer/HCC
- Published on Friday, 25 July 2008 00:00
- Written by Liz Highleyman
Two recently published studies produced promising data on experimental therapies for HCC: the systemic chemotherapy drug sorafenib (Nexavar), and combination therapy using doxorubicin-eluting beads plus radiofrequency ablation.
GLOBE Trial 2-Year Data Shows Telbivudine (Tyzeka) Is More Effective than Lamivudine (Epivir-HBV) for Chronic Hepatitis B
- Details
- Category: HBV Treatment
- Published on Friday, 27 February 2009 12:49
- Written by HIVandHepatitis.com
Several nucleoside/nucleotide analog agents have activity against hepatitis B virus (HBV), but the development of drug resistance can be a barrier to long-term treatment success. Newer agents, however, appear to produce more durable benefit than the old standard-of-care, lamivudine (Epivir-HBV). Telbivudine (Tyzeka) was approved by the U.S. Food and Drug Administration in October 2006. Approval was based in part on 52-week data from the pivotal GLOBE trial. Follow-up continued, and now 104-week safety and efficacy findings have been published in the February 2009 issue of Gastroenterology.
Association between ALT and HBV DNA Viral Load in Chronic Hepatitis B Patients Treated with Pegylated Interferon
- Details
- Category: HBV Treatment
- Published on Tuesday, 17 June 2008 14:01
- Written by Liz Highleyman
Association between ALT and HBV DNA Viral Load in Chronic Hepatitis B Patients Treated with Pegylated Interferonaminotransferase (ALT) is a key indicator of liver inflammation in individuals with chronic hepatitis B virus (HBV) infection. During interferon-based therapy, approximately 25%-40% of patients experience ALT "flares" (sudden increases), but the relationship between ALT level and treatment outcome is not well understood.
Adefovir (Hepsera) Prevents Post-transplant HBV Recurrence as well as HBIG
- Details
- Category: HBV Treatment
- Published on Tuesday, 27 January 2009 12:49
- Written by HIVandHepatitis.com
Liver transplantation is the only treatment for end-stage liver failure due to chronic hepatitis B virus (HBV) infection, but without preventive therapy, the virus typically quickly attacks the new liver, which can lead to complications, organ failure, and death.
Association between Hepatitis B and C Virus Infection and Extrahepatic Bile Duct Cancer
- Details
- Category: HBV Disease Progression
- Published on Friday, 13 June 2008 14:01
- Written by Liz Highleyman
It is well known that chronic infection with hepatitis B virus (HBV) or hepatitis C virus (HCV) can lead to advanced liver disease, including hepatocellular carcinoma (a form of primary liver cancer) over the course of years or decades. Now, a new study published in the April 15, 2008 International Journal of Cancer indicates that viral hepatitis may also promote development of cancer of the extrahepatic bile duct, which transports bile from the liver to the small intestine, joining with a similar duct from the gall bladder.
More Articles...
- EASL 2008: Sorafenib (Nexavar) Improves Outcomes in Patients with Hepatocellular Carcinoma
- Canadian Health Officials Warn against Use of Tebivudine (Tyzeka/Sebivo) in Combination with Interferons
- Long-term Adefovir (Hepsera) plus Emtricitabine (Emtriva) vs Adefovir Monotherapy for Chronic Hepatitis B
- Adefovir (Hepsera) for Treatment of Patients with Chronic Hepatitis B Resistant to Lamivudine (Epivir)
- CDC Reports Dramatic Declines in New Cases of Hepatitis A, B, and C
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