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Hepatitis B

Lack of Sleep May Compromise Hepatitis B Vaccine Response

People who got less than 6 hours of sleep per night showed significantly reduced antibody responses after hepatitis B virus (HBV) vaccination, a finding that may shed light on the well-known association between poor sleep and increased susceptibility to infectious disease, researchers reported in the August 1, 2012, issue of Sleep.alt

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July 28 Is World Hepatitis Day

Saturday, July 28, is World Hepatitis Day, an opportunity to raise awareness about life-threatening viral hepatitis. Over years or decades hepatitis B and C can progress to severe liver disease including cirrhosis and liver cancer, and viral hepatitis is a leading indication for liver transplants.alt

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HBV Genotype Affects Hepatitis B Disease Progression and Outcomes

Hepatitis B virus (HBV) genotype influences long-term outcomes including viral clearance, according to a Swedish study reported in the May 18, 2012, advance edition of the Journal of Clinical Virology. Genotype C in particular appears to be associated with more aggressive disease.alt

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EASL Publishes Revised Clinical Practice Guidelines for Chronic Hepatitis B

The European Association for the Study of the Liver (EASL) recently revised its clinical practice guidelines for the management of patients with chronic hepatitis B virus (HBV) infection. The new recommendations were announced at the International Liver Congress in April in Barcelona and published in the July 2012 Journal of Hepatology. alt

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Researchers Shed Light on how Hepatitis B Virus Causes Liver Cancer

Hepatitis B virus (HBV) is more often integrated in liver tumor cells than normal liver tissue cells, and multiple integrations may be linked to more aggressive disease progression and poorer survival, researchers reported in the May 27, 2012 advance online edition of Nature Genetics.alt

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FDA Will Review New Dynavax Hepatitis B Virus Vaccine

The U.S. Food and Drug Administration (FDA) has indicated that it will review for approval a new hepatitis B vaccine known as Heplisav.alt

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More than 2 Million People in U.S. May Have Chronic Hepatitis B

The prevalence of chronic hepatitis B virus (HBV) infection in the U.S. may be as high as 2.2 million -- greater than previously estimated -- with the highest numbers of cases occurring among foreign-born individuals, especially those from Asia and Africa.alt

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Researchers Grow Liver Tissue from Pluripotent Stem Cells

Japanese researchers have produced liver-like tissue from induced pluripotent stem cells in the laboratory that can process drugs like a human liver, according to a presentation at the 10th annual meeting of the International Society for Stem Cell Research last week in Yokohama.alt

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Korean Mummy Reveals Hepatitis B Genetic Clues

Genetic analysis of a liver sample from a mummified child found in Korea has revealed a distinct ancient form of a hepatitis B virus C2 genotype now common in Southeast Asia, researchers reported in the May 21, 2012, advance online edition of Hepatology.alt

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