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Hepatitis B

FDA Warns of Hepatitis B Reactivation Risk with Immune-suppressing Cancer Drugs

The U.S. Food and Drug Administration (FDA) announced this week that it has approved labeling changes for 2 monoclonal antibody cancer drugs, ofatumumab (Arzerra) and rituximab (Rituxan), adding a stronger "black box" warning that they may cause hepatitis B virus (HBV) reactivation.

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High Rate of New Hepatitis B Among African-Americans, Study Finds

Black Americans have a higher incidence of hepatitis B virus (HBV) infection than any other racial/ethnic group, including Asian-Americans, according to a review article in the July 1, 2013, advance edition of Clinical Gastroenterology and Hepatology.

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WHO Releases Global Policy Report on Prevention and Control of Viral Hepatitis

In advance of World Hepatitis Day (June 28), the World Health Organization (WHO) this week released its first country-by-country hepatitis survey, covering viral hepatitis prevention and control efforts in 126 member states.

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Human Stem Cells Used to Create Functional Liver Cells in Mice

Researchers have discovered a way to generate functional hepatocytes (liver cells) from human stem cells, which worked as expected and increased survival when transplanted into mice with acute liver injury, researchers reported in the July 9, 2013, advance online edition of Stem Cells and Development.

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IAS 2013: Many People Need Hepatitis B Treatment in the Gambia

About 8% of people tested through a community-based screening program in the Gambia have hepatitis B, and about 8% of these have advanced liver disease and meet European criteria for antiviral therapy, according to a report presented at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) this month in Kuala Lumpur.

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Hepatitis B Treatment with Entecavir Lowers Risk of Liver Cancer

Long-term treatment with entecavir (Baraclude) significantly reduces the chances of developing hepatocellular carcinoma compared with no treatment, and appears to lower the risk more than an older drug, especially for the most at-risk patients, according to a report in the July 2013 issue of Hepatology.

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DDW 2013: Does HBV Suppression Prevent Liver Disease Progression?

Chronic hepatitis B patients with cirrhosis may still experience liver disease progression even if they undergo antiviral treatment and achieve good virological response, according to a poster presented at the Digestive Disease Week meeting (DDW 2013) last month in Orlando.

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July 28 Is World Hepatitis Day

Sunday, July 28, is World Hepatitis Day, an opportunity to raise awareness about viral hepatitis and its consequences. The World Hepatitis Alliance theme for 2013 -- See No Evil, Hear No Evil, Speak No Evil -- emphasizes that hepatitis B and C are receiving inadequate attention worldwide, despite the large number of people affected and the high burden on healthcare systems.

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Low Vitamin D Linked to Greater Hepatitis B Virus Replication

Low blood levels of 25-hydroxyvitamin D were strongly associated with higher hepatitis B virus (HBV) viral load in a study of more than 200 untreated patients described in the May 22, 2013 advance online edition of Hepatology.

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