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HCV Disease Progression

Hepatitis C Liver Decompensation Remains a Problem for People with HIV Despite Good ART

People with HIV who are coinfected with hepatitis C virus (HCV) continue to have a higher risk for decompensated cirrhosis, or liver failure, even in the era of effective antiretroviral therapy (ART), according to a study published in the March 18 Annals of Internal Medicine. As such, they especially stand to benefit from new interferon-free hepatitis C treatments.

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Happy Holidays from HIVandHepatitis.com

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AASLD 2013: Aspirin and Cenicriviroc May Help Reduce Liver Fibrosis

Hepatitis C patients who took low-dose aspirin after liver transplantation experienced slower fibrosis progression, researchers reported at the AASLD Liver Meeting this month in Washington, DC. Two other studies showed that cenicriviroc -- a drug being developed for HIV treatment that blocks both CCR5 and CCR2 cell surface receptors -- had anti-inflammatory and anti-fibrotic activity in mice and rats.

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Coffee and Tea May Help Reduce Liver Inflammation in People with Hepatitis C

Chronic hepatitis C patients who drink caffeinated filtered coffee on a daily basis were more likely to have lower alanine aminotransferase (ALT) levels, indicating less liver inflammation, according to a study published in the December 11, 2013, edition of PLoS ONE. Black or oolong tea also appeared to have a beneficial effect.

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AASLD 2013: Hepatitis C Treatment Reduces Liver Cancer and Death, But Most Remain Untreated

Hepatitis C treatment that leads to viral suppression significantly reduces the likelihood of liver disease progression and liver-related mortality, but most patients remain untreated, according to a presentation at the 64th AASLD Liver Meeting last week in Washington, DC. Other studies found that a growing proportion of liver transplants are due to hepatocellular carcinoma, which can still occur even after treatment.

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