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Opioid Maintenance Therapy Linked to Lower Hepatitis C Rates for People Who Inject Drugs

Young drug injectors who undergo opioid agonist maintenance therapy using buprenorphine or methadone have a lower likelihood of becoming infected with hepatitis C virus (HCV) than those who continue injecting or use other types of substance use treatment, according to a study published in the October 27 edition of JAMA Internal Medicine.

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Studies Reveal HIV and HCV Epidemics Among Injection Drug Users in the Middle East and North Africa

At least one-third of countries in the Middle East and North Africa that historically have had low rates of HIV infection now have emerging epidemics largely attributable to injection drug use, according to a systematic review published in the June 17 edition of the open access journal PLoS Medicine. Rates of hepatitis C virus (HCV) infection also appear to be high and rising.

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CROI 2014: Monkey Studies Confirm Validity of Injectable PrEP

Two studies in monkeys of an injectable formulation of the third-generation integrase inhibitor drug GSK1265744 (or GSK744LA, where LA stands for "long-acting") have strengthened the evidence that it may work as pre-exposure prophylaxis (PrEP) in humans, researchers reported at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston. A Phase 2 study in humans will be starting soon.

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