Back HCV Populations Injection Drug Users

Direct-acting Antivirals Could Dramatically Reduce Hepatitis C Transmission among IDUs

Widespread use of new direct-acting antiviral agents (DAAs) for hepatitis C could dramatically lower the rate of HCV transmission among people who inject drugs in 3 hard-hit cities, according to a math model described in the March 28, 2013, issue of Hepatology.

They assumed that interferon-free regimens would produce 90% sustained virological response (SVR) with 12 weeks of treatment and would be available by 2015 -- all "realistic scenarios" based on the latest research.alt

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Naloxone Is Cost-effective Way to Prevent Heroin Overdose Deaths

Distributing naloxone more widely to heroin users would reduce the number of deaths due to overdose and would be a cost-effective intervention, according to a mathematical model described in the January 1, 2013,Annals of Internal Medicine. Providing naloxone to prescription opiate users would prevent even more deaths.

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ICAAC 2012: Hepatitis C Can Be Successfully Treated in Injection Drugs Users with or without HIV

HIV negative and HIV positive chronic hepatitis patients  in Vancouver with a history of injection drug use -- most of whom were on methadone maintenance -- achieved sustained response rates with interferon-based therapy similar to those of non-users, researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) last month in San Francisco. alt

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