HIV/AIDS Topics HIV-Related Conditions Liver & Kidney Disease
IAS 2017: Acute Kidney Injury Uncommon on Tenofovir, No Link Seen to Bone Breaks
- Details
- Category: HIV Treatment
- Published on Thursday, 17 August 2017 00:00
- Written by Gus Cairns
Doctors need to monitor patients regularly for kidney function if they are taking tenofovir disoproxil fumarate (TDF), especially if combined with ritonavir, according to a report at the 9th International AIDS Society Conference on HIV Science (IAS 2017) last month in Paris.
Johns Hopkins Team Performs Pioneering HIV+ to HIV+ Liver and Kidney Transplants
- Details
- Category: When to Start ART?
- Published on Wednesday, 30 March 2016 00:00
- Written by Liz Highleyman
Doctors at Johns Hopkins announced that they recently performed the first-ever liver transplant and the first kidney transplant in the U.S. from an HIV-positive donor to a recipient living with HIV, made possible by the 2013 HIV Organ Policy Equity (HOPE) Act. Both transplants were successful and the patients are doing "extremely well," infectious disease specialist Christine Durand said at a March 30 press conference.
CROI 2014: Tesamorelin Growth-Hormone Releaser Reduces Liver Fat in People with HIV
- Details
- Category: Metabolic Problems
- Published on Friday, 07 March 2014 00:00
- Written by Theo Smart
Tesamorelin, a synthetic form of growth-hormone-releasing hormone (GHRH), which the FDA has approved to reduce excess visceral abdominal fat in people living with HIV, also reduced associated liver fat in an HIV positive cohort chosen for abdominal adiposity, according to the results from a randomized, placebo-controlled trial presented at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston.
CROI 2015: Tenofovir, Atazanavir & Lopinavir Associated with Raised Risk of Chronic Kidney Disease
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- Category: Liver & Kidney Disease
- Published on Monday, 09 March 2015 00:00
- Written by Gus Cairns
Three antiretroviral drugs are associated with a slowly increasing rate of chronic kidney disease over time, researchers reported at the recent 2015 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle. Although the risk of developing chronic kidney disease was low for people with normal kidney function -- with fewer than 1% of patients in the large D:A:D cohort developing it -- the use of any of these drugs was associated with 2 to 3 times higher risk of kidney disease developing over the course of 5 years on the drug.
IAS 2013: End-Stage Kidney Disease Is More Common Among People with HIV
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- Category: Liver & Kidney Disease
- Published on Wednesday, 07 August 2013 00:00
- Written by Liz Highleyman
HIV positive people in the U.S. and Canada are nearly 4 times as likely to develop end-stage renal disease than HIV negative people in the general population, largely driven by a very high rate among blacks, researchers reported last month at the 7th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2013) in Kuala Lumpur.
HIV Rebound Linked to Liver Fibrosis Progression in HIV/HCV Coinfected
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- Category: Liver & Kidney Disease
- Published on Thursday, 05 February 2015 00:00
- Written by Liz Highleyman
HIV-positive people with hepatitis C virus (HCV) experienced progression to liver fibrosis if their HIV viral load rebounded above 1000 copies/mL or remained detectable on 2 consecutive tests, researchers reported in the January edition of HIV Medicine. Smaller transient HIV "blips," however, were not associated with worsening fibrosis. Optimized antiretroviral therapy, the study authors suggested, may protect the liver.
CROI 2013: HIV+ Men at Increased Risk for Co-morbid Conditions Regardless of Age
- Details
- Category: HIV-Related Conditions
- Published on Wednesday, 20 March 2013 00:00
- Written by Matt Sharp
Men with HIV in a large cohort of U.S. veterans were more likely to develop cardiovascular disease, end-stage kidney disease, and certain cancers compared with HIV negative people, but not at earlier ages, according to a report presented at the 20th Conference on Retroviruses and Opportunistic Infections this month in Atlanta.
HIVMA Issues Guidelines for Managing Chronic Kidney Disease in People with HIV
- Details
- Category: Liver & Kidney Disease
- Published on Wednesday, 08 October 2014 00:00
- Written by HIVMA
The HIV Medical Association (HIVMA) of the Infectious Diseases Society of America (IDSA) has released updated recommendations for HIV positive people with chronic kidney disease. The guidelines, published in the September 17 issue of Clinical Infectious Diseases, state that antiretroviral therapy (ART) is beneficial for such patients, but they should avoid tenofovir (Viread, also in the Truvada, Atripla, Complera, and Stribild coformulations), which can cause kidney impairment.
Tenofovir, Protease Inhibitors Linked to Kidney Impairment
- Details
- Category: HIV Treatment
- Published on Thursday, 28 February 2013 00:00
- Written by Liz Highleyman
Use of tenofovir disoproxil fumarate (TDF) is associated with reduced kidney function, though for most people the change is small, does not progress with continued exposure, and improves after stopping the drug, according to several recently published studies. Some analyses found that certain HIV protease inhibitors can also cause kidney problems.
More Articles...
- HIV+ People Should Be Able to Receive Organs from HIV+ Donors, Experts Say
- IAS 2011: Transplants Safe for HIV+ People but HCV Adds Risk
- Liver Fibrosis Common in HIV+ People without Viral Hepatitis
- People with HIV Have Higher Rate of Severe Liver Disease, Antiretroviral Therapy Cuts Risk
- Kidney Function Remains Stable among French HIV Patients on Long-term Antiretroviral Therapy
- Antiretroviral Therapy Is Not Responsible for Unexplained Liver Disease in HIV Patients without Viral Hepatitis Coinfection
- Advanced Liver Disease in People with HIV
- AASLD 2006: Liver Transplantation in HIV Positive Patients
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