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Treatment as Prevention

BHIVA 2017: Large Fall in London HIV Diagnoses Is Due to Combination Prevention, Not Just PrEP

The number of new HIV diagnoses among gay men attending 5 key London clinics fell substantially during 2015 and 2016, Valerie Delpech of Public Health England reported at the British HIV Association (BHIVA) conference last week in Liverpool.

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1. HIV Undetectable = Uninfectious

Evidence continues to accumulate showing that HIV-positive people on effective combination antiretroviral therapy (ART) with a consistently undetectable viral load have a very low -- perhaps as low as zero -- risk of transmitting the virus.

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AIDS 2016: More Confidence on Zero Risk -- Still No Linked HIV Infections in PARTNER Study

The PARTNER study, which 2 years ago generated headlines by establishing that the chance of an HIV-positive person with an undetectable viral load transmitting the virus was very low and quite possibly zero, released new data last week at the 21st International AIDS Conference (AIDS 2016) that further refined this estimate. The findings were also published in the July 12 New England Journal of Medicine.

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AIDS 2016: Large Test-and-Treat Study Fails to Show Impact on New HIV Infections

The first major research study of "test and treat" as a public health intervention to report its final results -- ANRS 12249 -- has found that the strategy failed to reduce new HIV infections in the African communities where it was provided, according to a report at the 21st International AIDS Conference (AIDS 2016) last week in Durban.

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AIDS 2016: SEARCH Study Exceeds 90-90-90 Targets After 2 Years of HIV Test-and-Treat

A large study that embeds "'test-and-treat" for HIV within a larger multi-disease prevention campaign in rural Kenya and Uganda has achieved 82% viral suppression after 2 years, and has already exceeded UNAIDS targets for viral suppression after 1 year of activity, investigators from the SEARCH study reported at the 21st International AIDS Conference (AIDS 2016) this week in Durban.

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