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Children & Adolescents

AIDS 2014: Worldwide Adolescent AIDS Deaths Rising, Especially Among Boys

While new HIV infections have declined among children, adolescents, and adults since 2000, HIV-related deaths have risen sharply among adolescents, especially 15- to 19-year-old males, Tyler Porth of UNICEF reported at the 20th International AIDS Conference last month in Melbourne.

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Adolescents Born with HIV May Have Higher Heart Disease Risk

Nearly half of adolescents with lifelong HIV infection were found to have evidence of coronary artery atherosclerosis, putting them at elevated risk for cardiovascular disease, according to a study published in the December 23, 2013, advance edition of Circulation.

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FDA Approves Oral Raltegravir for Children with HIV

The U.S. Food and Drug Administration (FDA) last month approved a new dosage form of the HIV integrase inhibitor raltegravir (Isentress). The new raltegravir oral suspension is indicated for pediatric patients age 4 weeks or older weighing 3-20 kg (about 7-44 lb).

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Updated Guidelines for Antiretroviral Treatment of Children with HIV

The Department of Health and Human Services this week updated its Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection. Changes to the children's guidelines include specific drug recommendations and information about a possible cure of an HIV-infected infant following very early treatment.

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Updated Pediatric HIV Opportunistic Infection Guidelines Emphasize Antiretroviral Therapy

The U.S. National Institutes of Health, Centers for Disease Control and Prevention, and other medical associations have released an updated version of Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children. The latest revision emphasizes the importance of timely antiretroviral therapy as a key to preventing and managing OIs in infants and children with HIV.

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