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IAS 2015: Estrogen May Block HIV Reactivation, Hints at Gender Differences in Viral Reservoirs

Estrogen receptors on cells may play a role in HIV latency and reactivation, and drugs targeting these receptors could potentially be used to either promote reactivation of integrated viral genes or keep them silent, according to research presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention and at the preceding IAS Towards an HIV Cure Symposium last month in Vancouver.

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IAS 2015: Broadly Neutralizing Antibodies Against HIV [VIDEO]

Broadly neutralizing antibodies that can recognize multiple strains of HIV may be one component of a combination strategy to achieve long-term HIV remission, experts said at a media briefing on HIV cure research at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention this week in Vancouver.

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IAS 2015: Zinc Finger Nuclease Genome Editing [VIDEO]

Researchers used a zinc finger nuclease protein to delete a gene for the CCR5 receptor from stem cells in monkeys, an advance that could play a role in efforts to achieve a functional cure for HIV, according to a report at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment, and Prevention last month in Vancouver.

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IAS 2015: Altered Cholesterol Metabolism May Protect Immune Cells of Non-Progressors

Enhanced cholesterol metabolism in certain immune cells may help explain why some people with HIV can naturally control the virus with little or no disease progression, according to research presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention and at the preceding IAS Towards an HIV Cure Symposium last month in Vancouver. The findings suggest that regulating cellular cholesterol metabolism may offer a new approach to controlling HIV and potentially achieving a functional cure, or long-term remission.

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IAS 2015: Targets Proliferate in HIV Cure Research

The Towards an HIV Cure two-day symposium has become a fixture in advance of the International AIDS Society conferences and the meeting last week in Vancouver featured a more varied range of experimental approaches than ever in the search for ways of eliminating HIV infection from the body.

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