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Pregnancy & HIV MTCT

Updated Guidelines for Pregnant Women with HIV and Preventing Mother-to-Child Transmission

The U.S. Department of Health and Human Services last week released an update to its Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States. Notable changes include discussion of antiretroviral treatment as prevention and pre-exposure prophylaxis (PrEP) for serodiscordant couples wishing to conceive, and a new section on options for perinatally infected women who are now pregnant themselves.

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IAS 2015: Implant and Injectable Hormonal Contraception Most Effective Methods for Women with HIV

Hormonal contraceptive methods are highly effective in reducing the risk of pregnancy in women living with HIV whether on antiretroviral therapy (ART) or not, according to an evaluation involving over 5000 women, according to a report at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver last month.

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IAS 2015: Cash Encourages Circumcision, Prevention of Mother-to-Child HIV Transmission

Cash compensation can improve the uptake of key HIV prevention services in sub-Saharan Africa, according to results from 2 randomized studies presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last month in Vancouver. A randomized trial conducted in Nyanza province, Kenya, showed that offering compensation in the form of food vouchers resulted in a significantly higher uptake of medical male circumcision, while a second randomized trial conducted in the Democratic Republic of Congo showed that providing modest cash incentives significantly increased retention in services for prevention of mother-to-child HIV transmission.

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IAS 2015: Intensification of ART Reduces Risk of Late-term Mother-to-Child HIV Transmission

Maternal and infant antiretroviral therapy (ART) intensification is very effective in preventing HIV transmission during labor and birth from pregnant women with HIV in Thailand who present late for care, with less than 8 weeks of standard ART, Marc Lallemant reported at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015) last month in Vancouver.

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IAS 2015: Raltegravir Prevents Mother-to-Child HIV Transmission During Late Pregnancy

Combination antiretroviral therapy containing the integrase inhibitor raltegravir (Isentress) appears safe and effective and may be an attractive option for treatment of pregnant women with HIV -- and potentially their infants -- to prevent perinatal transmission, according to study findings presented at the 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention last week in Vancouver.

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