HIV/AIDS Topics HIV-Related Conditions Bone Loss
CROI 2017: Bone Density Improves in People Who Switch from Tenofovir DF to Tenofovir Alafenamide
- Details
- Category: Bone Loss
- Published on Thursday, 16 March 2017 00:00
- Written by Liz Highleyman
After 3 years, tenofovir alafenamide (TAF) for first-line HIV treatment was better at suppressing viral load and safer for the bones and kidneys than the older tenofovir disoproxil fumarate (TDF), researchers reported at the 2017 Conference on Retroviruses and Opportunistic Infections (CROI) last month in Seattle. Another study showed that people with low bone density who switched from TDF to TAF saw improved bone health, including a reduction in osteoporosis.
CROI 2016: Tenofovir HIV Treatment Raises Risk of Broken Bones
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- Category: Bone Loss
- Published on Tuesday, 23 February 2016 00:00
- Written by Keith Alcorn
Treatment containing tenofovir is associated with a higher risk of bone fractures in people living with HIV, but a single infusion of zoledronic acid -- a drug used in the treatment of osteoporosis -- can protect against bone loss, a pair of studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2016) this week in Boston show.
Screening for Bone Fracture Risk Should Be Routine for HIV+ People over 40
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- Category: Bone Loss
- Published on Wednesday, 11 February 2015 00:00
- Written by Keith Alcorn
Screening for fracture risk should be a routine part of HIV care for all people over 40, and all postmenopausal women, all men over 50, and people at high risk for fractures of any age should undergo DEXA screening (a type of X-ray) to assess bone mineral density and their need for treatment, experts on bone disorders recommend in new guidelines published in the January 21 online edition of Clinical Infectious Diseases.
CROI 2016: Bone Density Recovers Quickly After Stopping Truvada PrEP
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- Category: Bone Loss
- Published on Tuesday, 23 February 2016 00:00
- Written by Keith Alcorn
Bone mineral density recovers within 6 months after stopping pre-exposure prophylaxis (PrEP) containing tenofovir, Robert Grant from the University of California at San Francisco reported on behalf of the iPrEx study at Conference on Retroviruses and Opportunistic Infections (CROI 2016) this week in Boston.
People with HIV Have Higher Bone Fracture Risk in Danish Study
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- Category: Bone Loss
- Published on Wednesday, 28 May 2014 00:00
- Written by Liz Highleyman
Being HIV positive was associated with a nearly 3-fold greater likelihood of bone fractures overall -- and a 9-fold higher risk of hip and spine fractures -- compared with HIV negative people, according to results from a large Danish population study described in the May 1 Journal of Acquired Immune Deficiency Syndromes.
IAS 2015: Bone Loss Slows, but Continues Long-term in HIV-positive People on Antiretroviral Therapy
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- Category: Bone Loss
- Published on Wednesday, 09 September 2015 00:00
- Written by Liz Highleyman
People with HIV experienced a decrease in bone density at the hip and spine during their first 2 years after starting antiretroviral therapy (ART). While bone loss slowed after 96 weeks, it continued to decline more rapidly among HIV-positive people compared with the usual age-related bone loss seen in HIV-negative people over 7 years, researchers reported at the recent 8th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Vancouver.
CROI 2014: Vitamin D and Rosuvastatin Improve Bone Loss in People with HIV
- Details
- Category: Bone Loss
- Published on Tuesday, 08 April 2014 00:00
- Written by Liz Highleyman
A combination of high-dose vitamin D and calcium may help reduce bone loss after starting antiretroviral therapy (ART), according to a presentation at the Conference on Retroviruses and Opportunistic Infections (CROI 2014) last month in Boston. A related study found that rosuvastatin increased hip bone mineral density in HIV positive people on ART, though insulin resistance worsened.
CROI 2015: FRAX Fracture Prediction Tool Underestimates Fracture Risk in Men with HIV
- Details
- Category: Bone Loss
- Published on Tuesday, 17 March 2015 00:00
- Written by Theo Smart
The Fracture Risk Assessment Tool (FRAX), an online tool developed by the World Health Organization and used to help guide decisions about who to screen or treat in order to prevent bone fractures, underestimates overall risk of fracture in people living with HIV -- even with an adjustment experts have recommended to improve its accuracy for people with HIV -- according to an analysis of the Veterans Aging Cohort Study Virtual Cohort (VACS-VC) reported at the recent 2015 Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle.
CROI 2014: Researchers Discuss HIV, Aging, and Frailty
- Details
- Category: HIV-Related Conditions
- Published on Friday, 04 April 2014 00:00
- Written by Theo Smart
People living with HIV are at greater risk of geriatric syndromes such as frailty and difficulty with daily activities than HIV negative people of the same age -- and this can have a significant effect upon their quality of life as they age, according to several studies presented at the 14th Conference on Retroviruses and Opportunistic Infections (CROI 2014) last month in Boston.
More Articles...
- CROI 2014: Newborns Exposed to Tenofovir Have Lower Bone Content [VIDEO]
- Highlights from 2013 ICAAC, IDWeek, and EACS Meetings
- Low CD4 Count Raises Risk of Heart Attack, Bone Loss
- IDWeek 2013: HIV+ People Not on Antiretrovirals Are Prone to Inflammation-related Bone Loss
- Low CD4 Count at Start of HIV Treatment Linked to Greater Bone Loss
- IAS 2013: Studies Look at Second-Line Bone Changes, Fractures, and HIV- and HCV-Related Bone Loss
- IAS 2013: Second-line HIV Therapy with NRTIs Linked to Bone Loss [VIDEO]
- Bone Loss and Fracture Risk are 'Modest' among HIV+ People, Linked to Tenofovir, Smoking, and HCV
- HIV Treatment Interruption Associated with Reduced Bone Loss in SMART Trial
- Study Finds Increased Fractures in First 2 Years after Starting Antiretroviral Treatment
- ICAAC 2012: Simplified Abacavir/Atazanavir Combo Keeps HIV Suppressed, May Help Bones
- ICAAC 2012: Bone Loss Is Common in French HIV Cohort, Linked to Older Age and Lower Weight
- AIDS 2012: HIV+ Men Prone to Bone Fractures at Earlier Age
- HIV/HCV Coinfected People Have Higher Risk of Hip Fractures
- Young Men on Antiretroviral Therapy at Risk for Bone Loss
- Bisphosphonate Drugs Linked to Atypical Femur Fractures, but Absolute Risk is Small
- Zoledronate Protects HIV Positive Men against Bone Loss for at Least 5 Years
- CROI 2012: Switching to Tenofovir Increases Bone Turnover, Raltegravir Can Improve Bone Density
- Conflicting Data on Bone Fracture Link to HIV Meds
- Vitamin D May Improve Bone Health in Young HIV+ People Taking Tenofovir
- HIV+ People on ART Have Stable Bone Density after Short-term Loss
- FDA Considers Limits on Osteoporosis Drugs Due to Fracture Risk
- Age-Related Fractures Due to Reduced Bone Quality as well as Quantity
- IAS 2011: Doubt Remains if HIV Therapy Increases the Risk of Fragility Fractures
- IAS 2011: Coronary Artery Calcification Linked to Bone Loss
- Low CD4 Count Linked to Bone Fractures
- CROI 2011: HIV/HCV Coinfected People Have Higher Risk of Bone Loss
- Prevention Task Force Recommends Wider Bone Screening for Older Women
- People with HIV Have Increased Bone Fracture Risk
- Is Bone Loss Related to Immune Reconstitution in People on ART?
- FDA Warns of Unusual Femur Fractures in People Taking Bisphosphonates for Osteoporosis
- Bone Loss and Low Vitamin D Levels Are Common among People with HIV
- AIDS 2010: Majority of HIV Positive People on Antiretroviral Therapy May Have Reduced Bone Density
- CROI 2011: Low Vitamin D Levels Less Likely with Rilpivirine than Efavirenz
- IAS 2009: Vitamin D Deficiency is Common among HIV Positive People and Is Associated with NNRTI Use, Black Race, and Smoking
- Protease Inhibitor Regimens Associated with Greater Decrease in Bone Mineral Density than NNRTI Regimens in Treatment-naive HIV Patients
- Zoledronate Improves Bone Loss in People with HIV
- ICAAC 2008: Continuous HAART Associated with Elevated Risk of Bone Loss in SMART Treatment Interruption Trial
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