HIV Vaccines
HIV Vaccines
AIDS 2016: New HIV Vaccine Efficacy Trial Set to Start this Year
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- Category: HIV Vaccines
- Published on Friday, 22 July 2016 00:00
- Written by Gus Cairns
A new efficacy trial for an HIV vaccine -- only the seventh ever conducted in the history of the epidemic -- will start this November, delegates heard at the 21st International AIDS Conference (AIDS 2016) taking place this week in Durban. The HVTN 702 study will enroll 5400 men and women in southern Africa, and is planned to last for 4 years. In May it was announced that a pilot study, HVTN 100, had met the criteria for the vaccine being taken forward into the larger study. But this week was the first time researchers revealed how well it had met those criteria.
Experimental HIV Vaccine to Enter Large Clinical Trial in South Africa
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- Category: HIV Vaccines
- Published on Thursday, 26 May 2016 00:00
- Written by NIH
An investigational vaccine that showed promise in an earlier study will advance to a large-scale efficacy trial at 15 sites in South Africa, the U.S. National Institutes of Health (NIH) announced on May 18, marking HIV Vaccine Awareness Day. The new trial, HVTN 702, designed to determine if the vaccine is safe, well-tolerated, and effective at preventing HIV infection, is due to start this November, with results expected in 4 years.
Studies Advance Understanding of Broadly Neutralizing Antibodies Against HIV
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- Category: HIV Vaccines
- Published on Thursday, 09 July 2015 00:00
- Written by Rockefeller University
Three recent studies funded by the National Institutes of Health have shed further light on broadly neutralizing antibodies that may play a role in developing an effective HIV vaccine. The studies demonstrated techniques for stimulating immune cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory, or had the potential to evolve into such antibodies, according to a National Institute of Allergy and Infectious Diseases press release.
Model Suggests HIV Vaccine Could Play Key Role in Ending AIDS
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- Category: HIV Vaccines
- Published on Wednesday, 20 January 2016 00:00
- Written by Liz Highleyman
Even a modestly effective HIV vaccine would likely be cost-effective and could make a major contribution to a sustainable response to the global HIV/AIDS epidemic, especially in combination with the scale-up of other interventions including prompt antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP), according to a report in the January 5 edition of PLoS ONE.
Vaccine Combo Demonstrates Protection Against HIV-like Virus in Monkey Study
- Details
- Category: HIV Vaccines
- Published on Friday, 03 July 2015 00:00
- Written by Beth Israel Deaconess
Administering a 2-part prime-boost vaccine prevented infection in half of a dozen rhesus monkeys repeatedly exposed to simian immunodeficiency virus (SIV), and antibody responses against viral envelope proteins appeared to be the key to protection, according to a study published in the July 2 advance edition of Science magazine.
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