Search for a Cure
Researchers Observe Sustained Remission in Monkeys with HIV-Like Virus
- Details
- Category: Search for a Cure
- Published on Sunday, 16 October 2016 00:00
- Written by Liz Highleyman
Researchers have induced sustained remission of simian immune deficiency virus (SIV), a relative of HIV, in macaque monkeys treated with antiretroviral therapy (ART) and an antibody-based therapy used to treat inflammatory bowel disease, according to a report in the October 14 edition of Science. The monkeys not only had undetectable viral load for up to nearly 2 years after stopping treatment, but they also showed replenishment of key immune cells in the gut.
Media Reports of a British HIV Cure Breakthrough Are Premature
- Details
- Category: Search for a Cure
- Published on Monday, 03 October 2016 00:00
- Written by Keith Alcorn
The Sunday Times yesterday reported that HIV had become undetectable in the blood of one man taking part in the RIVER study, a trial of an intensive treatment regimen designed to test whether it is possible to reduce levels of HIV-infected cells in the bodies of people recently infected with HIV. The Sunday Times reported that British scientists are on the "brink of an HIV cure." But in fact, the study is still in its early stages, participants are still on antiretroviral treatment, and it will not be able to describe participants as "cured" until extensive follow-up has taken place.
AIDS 2016: HIV Will Only Be Cured with Combined Approaches, Conference Delegates Hear
- Details
- Category: Search for a Cure
- Published on Thursday, 08 September 2016 00:00
- Written by Gus Cairns
Curing people of HIV infection will have to involve combinations of drugs and approaches, just as HIV treatment does, delegates heard at the Towards an HIV Cure workshop held in advance of the recent 21st International AIDS Conference (AIDS 2016) in Durban. The reason is the same, too: HIV can easily develop resistance to single agents, even ones as sophisticated as broadly neutralizing antibodies and gene-editing enzymes.
AIDS 2016: Realism Needed About the Benefits and Risks of Taking Part in HIV Cure Research
- Details
- Category: Search for a Cure
- Published on Thursday, 08 September 2016 00:00
- Written by Roger Pebody
A significant proportion of people living with HIV would be willing to take part in a study towards a cure for HIV, according to research presented at the recent 21st International AIDS Conference (AIDS 2016) in Durban. However, some potential participants may not fully understand that taking part in an early-phase study is highly unlikely to afford any personal clinical benefit, but might have the potential to cause harm.
AIDS 2016: International AIDS Society Releases New HIV Cure Research Strategy
- Details
- Category: Search for a Cure
- Published on Thursday, 04 August 2016 00:00
- Written by International AIDS Society
The International AIDS Society (IAS) released an update to its strategy to guide HIV cure research. The strategy, authored by the leading researchers in the field, was published in the July 11 online edition of Nature Medicine and discussed at the IAS Towards an HIV Cure Symposium preceding the 21st International AIDS Conference last month in Durban.