HIV/AIDS Topics ICAAC 2012: People with Low-level Viral Load Are at Risk for Treatment Failure and Poor CD4 Recovery
- Details
- Category: HIV Treatment
- Published on Wednesday, 26 September 2012 00:00
- Written by Liz Highleyman
Individuals who still have low levels of plasma HIV RNA despite taking antiretroviral therapy (ART) may experience treatment failure, and those with HIV residual DNA in their T-cells may not achieve expected CD4 cell gains, according to 2 studies presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this week in San Francisco. 
AIDS 2012: More People Starting HIV Treatment, Lower Viral Load in NA-ACCORD Study
- Details
- Category: HIV Treatment
- Published on Tuesday, 04 September 2012 00:00
- Written by Liz Highleyman
More than 80% of HIV patients in the large North American ACCORD study are receiving combination antiretroviral therapy (ART), about 70% have suppressed viral load -- up from less than 50% in 2000 -- and the median age at the time of death rose by 6 years, researchers reported at the recent XIX International AIDS Conference (AIDS 2012) in Washington, DC.
AIDS 2012: Elite Control and Immune Activation in People with HIV and Hepatitis C
- Details
- Category: Non-Progression & Elite Controllers
- Published on Tuesday, 04 September 2012 00:00
- Written by Liz Highleyman
HIV "elite controllers" in a large women's study were found to still have low-level plasma HIV viral load, which could contribute to persistent immune activation and inflammation, researchers reported at the XIX International AIDS Conference (AIDS 2012) last month in Washington, DC. A series of related studies showed that immune activation was greater in people with HIV and hepatitis C coinfection, and that HIV controllers were also more likely to clear HCV -- though it is not clear why. 
Lack of Food Linked to More Hospitalizations among HIV+ People with Unstable Housing
- Details
- Category: HIV Disease Progression
- Published on Tuesday, 04 September 2012 00:00
- Written by Liz Highleyman
Homeless and marginally housed people with HIV in San Francisco who experienced "food insecurity" -- lack of stable access to sufficient nutrition -- were more likely to visit the emergency department and more likely to be hospitalized than people with a steady source of adequate food, researchers reported in the August 18, 2012, advance online edition of the Journal of General Internal Medicine. 
AIDS 2012: Incomplete CD4 T-Cell Response to ART Raises Mortality Risk
- Details
- Category: HIV Treatment
- Published on Tuesday, 21 August 2012 00:00
- Written by Liz Highleyman
Having fewer than 700 CD4 cells/mm3 and hepatitis C coinfection were associated with greater risk of death in a study of U.S. veterans, researchers reported at the recent XIX International AIDS Conference (AIDS 2012) in Washington, DC, suggesting that it may be beneficial to start antiretroviral treatment before CD4 counts fall to this level. 
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