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Severe Seroconversion Symptoms Predict Faster HIV Disease Progression

People who experience more severe symptoms or who have lower CD4 T-cell counts when they first become infected with HIV are more likely to experience faster disease progression later on, according to an international study described in the November 14, 2013, edition of PLoS Medicine.

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Nutritional Supplements Beneficial for HIV+ People Who Do Not Yet Need ART

HIV positive people with CD4 cell counts above 350 cells/mm3 who have not yet started antiretroviral therapy (ART) may reduce their risk of disease progression, immune system decline, and death if they take a multivitamin and selenium supplement, according to a study from Botswana published in the November 27, 2013, issue of JAMA.

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Food Insecurity Predicts Worse Outcomes for People with HIV

Lack of adequate nutrition was associated with reduced adherence to antiretroviral treatment, incomplete viral load suppression, and lower CD4 cell counts among HIV positive people in both Uganda and San Francisco, according to 2 recently published studies.

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New HIV Strain May Lead to Faster Disease Progression

A newly identified natural recombinant form of HIV, dubbed A3/02, was associated with nearly a 3-fold higher risk of progression to AIDS and AIDS-related death -- as well as a shorter time from seroconversion to AIDS or death --compared with 2 more common types found in West Africa, researchers reported in the August 9 advance edition of the Journal of Infectious Diseases.

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Increased Risk of AIDS-defining Illnesses Seen Even at CD4 Counts of 500-750

HIV positive people with CD4 T-cell counts in the 500-749 cells/mm3 range still have a higher risk of AIDS-defining illnesses -- especially cancers -- compared to those with more than 1000 cells/mm3, although the risk is quite low, according to a study published in the August 6, 2013, advance edition of Clinical Infectious Diseases. These findings offer further evidence of the benefits of prompt antiretroviral treatment.

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