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Gay Men Better at Predicting When They Won't Have Sex than When They Will

A study in which a group of HIV negative gay and bisexual men from New York City were asked to predict each day whether they would have sex the following day, and then compared their prediction with what actually happened, found that men generally overestimated the likelihood they would have sex. This study, published in the April 1 Journal of Acquired Immune Deficiency Syndromes, suggests possible pre-exposure prophylaxis (PrEP) dosing strategies.

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Meta-Analysis Shows Injectable Hormonal Contraception Linked to HIV Infection Risk

Women who use the long-acting injectable contraceptive Depo-Provera had a modest but significant increase in the risk of contracting HIV infection, according to a meta-analysis of 12 studies published in the January 8Lancet Infectious Diseases. However, there was no increase in risk for women using birth control pills.

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Semen May Enhance HIV Infectivity and Impair Microbicide Effectiveness

A component in semen appears to increase the likelihood of sexual transmission of HIV, and furthermore may enable the virus to over-power topical microbicides designed to prevent infection, according to a study published in the November 12 edition of Science Translational Medicine. This may be one of the factors explaining why drugs that block HIV infection in laboratory experiments have not worked in real-world settings, the researchers suggested.

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CDC Researchers Publish Estimate of Effectiveness of Condom Use for Gay Men

A paper published this month in the Journal of Acquired Immune Deficiency Syndromes finally makes publicly available a study-- originally reported nearly 2 years ago from the 2013 Conference on Retroviruses and Opportunistic Infections but until now unobtainable even as an abstract -- which gives an estimate for the effectiveness of 100% condom use as the strategy of choice for the prevention of HIV infection among gay men. The CDC researchers estimate that condoms used consistently stop 7 out of 10 HIV infections acquired through anal sex between men.

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New Studies Offer More Insight on HIV Sexual Transmission and Prevention

A new estimate puts the likelihood of HIV transmission via receptive anal sex at 138 per 10,000 acts, but looking at probabilities over a longer period provides a better understanding of risk than per-act probabilities, according to a pair of studies in the May 6 advance online edition of AIDS. Mathematical models showed that combining prevention methods -- especially those that include antiretroviral treatment-as-prevention or PrEP -- can greatly reduce the risk of transmission.

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