- Category: HIV Prevention
- Published on Monday, 12 May 2014 00:00
- Written by UCSF
Participants in the Stonewall Project, a harm reduction-based substance use program, reduced their use of methamphetamine and cocaine and engaged in less risky sexual behavior that could lead to HIV transmission, according to a pair of studies described in the April 14 online edition of the Journal of Urban Health.
Harm reduction aims to help people avoid the detrimental consequences of drug use -- such as infection with HIV or viral hepatitis -- while not requiring them to achieve complete abstinence. This study of more than 200 methamphetamine-using men who have sex with men looked at changes in self-reported substance use, sexual risk-taking, and HIV care.
The researchers saw reductions in cocaine or crack and methamphetamine use, though marijuana use increased. Participants reported less sexual risk behavior while using meth. About half of HIV positive people started or consistently used antiretroviral therapy, leading to viral load suppression.
"Taken together, these studies are among the first to observe that clients may reduce stimulant use and concomitant sexual risk-taking behavior during harm reduction substance abuse treatment," the authors concluded.
Below is an edited excerpt from a University of California San Francisco press release describing the study findings in more detail.
Harm-Reduction Program Optimizes HIV/AIDS Prevention, UCSF Study Shows
April 18, 2014 -- New research from UC San Francisco and the San Francisco AIDS Foundation has found that clients participating in a harm-reduction substance use treatment program, the Stonewall Project, decrease their use of stimulants, such as methamphetamine, and reduce their sexual risk behavior.
Harm reduction is a public health philosophy and strategy designed to reduce the harmful consequences of various, sometimes illegal, human behaviors such as the use of alcohol and other drugs regardless of whether a person is willing or able to cease that behavior.
"We found that even when participants were using methamphetamine, they reported engaging in HIV risk-reduction strategies such as having fewer anal sex partners after enrolling in Stonewall," said the study’s lead investigator, Adam W. Carrico, PhD, UCSF assistant professor of nursing.
The research findings appear online on April 18 in the Journal of Urban Health. The Stonewall Project, a San Francisco AIDS Foundation program, serves substance-using gay and bisexual men as well as other men who have sex with men. Stonewall implements evidence-based, cognitive-behavioral substance use treatment from a harm-reduction perspective. At Stonewall, clients have the option of abstinence, but may also use harm-reduction strategies such as transitioning to less potent modes of administration (e.g., injecting to snorting) or reducing sexual risk taking while they are under the influence.
Some sexual risk-reduction strategies delivered by the Stonewall Project are condom use promotion during sex, seroadaptive behaviors (having sex in ways that reduces the risk of acquiring or transmitting HIV), and decreasing the number of sex partners.
"We showed Stonewall can address stimulant use, a key barrier to HIV prevention and care, without insisting on abstinence. Our program, which is based on a willingness to work with clients regardless of their ability and/or willingness to stop using and teach them better ways to take care of themselves and improve their lives, has been borne out by these findings," said study co-investigator, Michael D. Siever, PhD, founder of the Stonewall Project.
Two-thirds of the 211 methamphetamine-using men who have sex men enrolled in the study were HIV positive, and there was some evidence to suggest that Stonewall’s harm reduction counseling may also assist men in taking their anti-HIV medications effectively enough to achieve an undetectable level of HIV in their blood.
"By helping our HIV-positive clients succeed in treating their HIV, we’re not only improving their health, but also reducing their likelihood of transmitting the virus," said study co-investigator, Michael V. Discepola, MA, director of the Stonewall Project at SFAF.
The next step following the findings of this research would be conducting a larger randomized controlled trial comparing abstinence-based and harm reduction approaches, added Carrico.
AW Carrico, A Flentje, VA Gruber, et al. Community-Based Harm Reduction Substance Abuse Treatment with Methamphetamine-Using Men Who Have Sex with Men. Journal of Urban Health. April 18, 2014 (Epub).
J Sheehy, University of California San Francisco. Harm-Reduction Program Optimizes HIV/AIDS Prevention, UCSF Study Shows. Press release. April 18, 2014.