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CROI 2015: Treatment Cascades and Viral Load Surveys Inform ART as Prevention in Africa

Reaching ambitious HIV prevention targets in South Africa will require intensified efforts to engage and retain men and young people in care, in order to increase the proportion of people on HIV treatment with suppressed viral load, according to a national study presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2015) last week in Seattle. Another study, conducted in 3 countries in sub-Saharan Africa, showed that to maximize the preventive effect of antiretroviral therapy (ART), efforts to expand treatment coverage need to focus on those with the highest viral load off treatment -- mainly people who are already eligible for treatment under current guidelines.

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UNAIDS: HIV Epidemic Will Spring Back without Near-Universal Diagnosis and Treatment

Adopting "fast-track" targets could avert more than 28 million new HIV infections and prevent 21 million AIDS-related deaths by 2030, according to this year's UNAIDS World AIDS Day Report. However, if the response is not rapidly scaled-up over the next 5 years to achieve near-universal diagnosis and treatment, the epidemic is likely to "spring back" with an even higher rate of new HIV infections than today, the report warns.

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AIDS 2014: Global ART Demand Projected to Reach 16.8 Million by 2016

The projected demand for antiretroviral therapy (ART) will increase to 16.8 million person-years by the end of 2016 in low- and middle-income countries, including 15.7 million person-years of adult and 1.1 million person-years of pediatric formulations, according to a study presented on behalf of the global ARV Forecasting Technical Working Group at the 20th International AIDS Conference(AIDS 2014) last month in Melbourne.

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UNAIDS: "Fast Track" Strategy Could Help End AIDS Epidemic by 2030

A rapid acceleration of HIV prevention and treatment efforts over the next 5 years directed at people most at risk in high prevalence areas could help turn the tide in the AIDS epidemic, according to participants at a recent high-level meeting during the 69th United Nations General Assembly. If fully implemented, this approach could potentially prevent 18 million new HIV infections and 11 million deaths by 2030, as well as reducing future costs.

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UNAIDS Gap Report Finds Half of HIV+ People Worldwide Are Unaware of Status

Half of people living with HIV worldwide -- or approximately 19 million -- do not know they are infected, preventing them from receiving life-saving treatment and contributing to viral transmission, according to the latest UNAIDS Gap Report released in advance of the 20th International AIDS Conference last week in Melbourne. The report also outlines progress, including the 13 million people who had access to antiretroviral therapy at the end of 2013.

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