- Category: Search for a Cure
- Published on Monday, 30 July 2012 00:00
- Written by Gregory Fowler
Timothy Ray Brown -- better know as the "Berlin Patient," the first person known to be cured of HIV -- launched a new foundation to raise funds for HIV cure research at the XIX International AIDS Conference (AIDS 2012) last week in Washington, DC. He took the opportunity to announce that he is still free of HIV.
[Timothy Brown press conference, 7/24/12]
In 2006 Brown received the first of 2 bone marrow transplants to treat leukemia from a donor lacking CCR5 co-receptors (one of the gateways HIV uses to enter cells). He stopped taking antiretroviral therapy (ART) before the first operation, and 5 years later still does not have replicable virus in his blood, immune cells, gut, or other tested tissues.
At a press conference announcing the Timothy Ray Brown Foundation on July 24, Brown reaffirmed that despite some recent speculation to the contrary, he remains cured of HIV according to his doctors.
At AIDS 2012 Daniel Kuritzkes and colleagues reported on 2 patients who show no traces of HIV after receiving stem cell transplants for lymphoma from donors with normal CCR5, using milder chemotherapy that enabled them to remain on ART.
"Words cannot begin to express my joy that 2 other men may have been cured of HIV," Brown said in a media statement. "This reinforces my determination and belief that we must fulfill my foundation’s central mission of investing in cutting-edge therapies and treatments to advance AIDS cure research. As I have said many times before, I want everyone to be cured of this disease."
T Henrich, G Sciaranghella, JZ Lee, DR Kuritzkes, et al. Long-term reduction in peripheral blood HIV-1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation in two HIV-positive individuals. XIX International AIDS Conference. Washington, DC, July 22-27, 2012.Abstract THAA0101.
Timothy Ray Brown Foundation. Timothy Ray Brown (The Berlin Patient) Reacts To Breaking News That Two More Men Hopefully Cured Of AIDS. Press release. July 26, 2012.