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Injection Drug Users

Hepatitis C Infections Fall after Harm Reduction Scale-up in Scotland

Hepatitis C virus (HCV) incidence among people who inject drugs declined rapidly after national scale-up of harm reduction interventions such as syringe exchange in Scotland, according to a report published in the August 11 edition of PLoS ONE. Changes in HCV prevalence, however, are lagging behind.

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AIDS 2014: Harm Reduction Funding Is Meeting Only 7% of Global Need

International donors are investing only 7% of what is needed to provide adequate harm reduction coverage for people who inject drugs, according to findings from a report presented this week at the 20th International AIDS Conference in Melbourne. A global commitment to re-balance spending on drug control and harm reduction is essential in order to achieve control of HIV and viral hepatitis among drug injectors, several speakers told the conference.

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CROI 2014: Monkey Studies Confirm Validity of Injectable PrEP

Two studies in monkeys of an injectable formulation of the third-generation integrase inhibitor drug GSK1265744 (or GSK744LA, where LA stands for "long-acting") have strengthened the evidence that it may work as pre-exposure prophylaxis (PrEP) in humans, researchers reported at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston. A Phase 2 study in humans will be starting soon.

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Studies Reveal HIV and HCV Epidemics Among Injection Drug Users in the Middle East and North Africa

At least one-third of countries in the Middle East and North Africa that historically have had low rates of HIV infection now have emerging epidemics largely attributable to injection drug use, according to a systematic review published in the June 17 edition of the open access journal PLoS Medicine. Rates of hepatitis C virus (HCV) infection also appear to be high and rising.

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CROI 2014: Long-acting GSK744 Protects Monkeys against HIV-like Virus [VIDEO]

A long-acting injectable formulation of the next-generation integrase inhibitor GSK1265744 protected monkeys from infection via vaginal or anal exposure to a hybrid human-simian virus, according to 2 studies presented at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this week in Boston. These promising findings suggest this may be a future approach to pre-exposure prophylaxis (PrEP).

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