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HIVR4P 2016: Rings, Films or Inserts? Prevention Products Need to Make Sense in Women's Lives

"We need to think outside of the box," Sharon Hillier of the Microbicide Trials Network told participants at the HIV Research for Prevention (HIVR4P 2016) conference this week in Chicago. Researchers should not be aiming to develop the most scientifically elegant solution for HIV prevention, but should "figure out how to make products that can really fit into people’s lives."

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HIVR4P 2016: New Microbicide Enema Achieves High Levels of Drug in Rectal Tissues in Monkeys

Rectal microbicides that protect against HIV transmission via anal sex are a bigger technical challenge than vaginal ones. The rectal lining is more delicate than the vaginal lining, so safety has been an issue; research has shown that many of the gel formulations used in lubricants damage rectal cells and may actually enhance HIV transmission.

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HIVR4P 2016: Vaginal and Rectal Bacteria May Influence HIV Transmission and Microbicide Efficacy

A number of presentations at the HIV Research for Prevention Conference (HIVR4P 2016) this week in Chicago looked at the influence of vaginal bacteria on HIV susceptibility, with one study finding that vaginal bacteria may have profound effects on levels of certain drugs used as microbicides -- but not others. A poster at the conference also looked at bacteria in the rectum in gay men, finding a correlation between condomless anal sex and changes in the predominant bacterial species which may similarly increase susceptibility to HIV infection.

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Coverage of HIV Research for Prevention Conference (HIVR4P 2016)

HIVandHepatitis.com coverage of the 2016 HIV Research for Prevention Conference (HIVR4P 2016), October 17-21, in Chicago.

Conference highlights include current and experimental pre-exposure prophylaxis (PrEP), microbicide rings and other options, and investigational HIV vaccines.

Full listing of coverage by topic

HIVR4P 2016 website

10/22/16

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HIVR4P 2016: Policymakers' Inaction is Leading People to Take "PrEP in the Wild"

An increasing number of gay men and others at risk for HIV are seeking to protect their health with pre-exposure prophylaxis (PrEP), but the lack of PrEP provision and regulatory approval in many countries is leading people to take it without medical supervision and on an ad-hoc basis. This will undermine the safety and effectiveness of PrEP, said Jerome Galea as he presented results of the PrEP in the Wild survey at the HIV Research for Prevention conference (HIVR4P 2016) this week in Chicago.

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